2,3-HEXANEDIONE Property

Melting point:

-30 °C

Boiling point:

128 °C(lit.)

Density 

0.934 g/mL at 25 °C(lit.)

vapor density 

3.9 (vs air)

vapor pressure 

10 mm Hg ( 20 °C)

refractive index 

n20/D 1.412(lit.)

FEMA 

2558 | 2,3-HEXANEDIONE

Flash point:

83 °F

storage temp. 

Store below +30°C.

solubility 

H2O: soluble (slightly soluble)

Odor

at 1.00 % in dipropylene glycol. dry sweet caramel butter oily fatty creamy phenolic fruity

Odor Type

buttery

explosive limit

1.2-5.9%(V)

Water Solubility 

Partly miscible in water.

JECFA Number

412

BRN 

1699896

Stability:

Stable. Flammable. Incompatible with strong bases, strong oxidizing agents.

LogP

-0.27

CAS DataBase Reference

3848-24-6(CAS DataBase Reference)

EPA Substance Registry System

2,3-Hexanedione (3848-24-6)

Safety

Hazard Codes 

Xi

Risk Statements 

10-36/37/38

Safety Statements 

26-36/37/39-16

RIDADR 

UN 1224 3/PG 3

WGK Germany 

2

RTECS 

MO3140000

Autoignition Temperature

245 °C

TSCA 

Yes

HazardClass 

3

PackingGroup 

III

HS Code 

29141990

Toxicity

LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 5000 mg/kg

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P314Get medical advice/attention if you feel unwell.

2,3-HEXANEDIONE Chemical Properties,Usage,Production

Description

2,3-Hexanedione has a powerful, creamy, sweet, and buttery odor (less than diacetyl) and a buttery, cheese taste. It may be synthesized from propionyl aldehyde condensed over ethyl acetylacetate;the resulting product is then oxidized (H2O2 and sodium tungstate), hydrolyzed, and finally decarboxylated to 2,3-hexanedione; from methyl butyl ketone and ethyl propyl ketone by way of the monoxime; also from acetoxy mesityl oxide.

Chemical Properties

yellow liquid

Chemical Properties

2,3-Hexanedione has a powerful, creamy, sweet and buttery odor (less than diacetyl) and a buttery cheese taste.

Occurrence

Reported found in fermented soybean, peach, roasted chicken, beer, coffee, shoyu and clam.

Uses

2,3-Hexanedione is used to evaluate the influence of xanthan concentration on the release of aroma compounds in xanthan-thickened food model systems. It reacts with ethylenediamine to yield macrocyclic tetradentate 12-membered nitrogen donor (N4) ligand.

Uses

2,3-Hexanedione was used to evaluate the influence of xanthan concentration on the release of aroma compounds in xanthan-thickened food model systems.

Definition

ChEBI: An alpha-diketone that is hexane substituted by oxo groups at positions 2 and 3 respectively.

Preparation

From propionyl aldehyde condensed over ethyl acetylacetate; the resulting product is then oxidized (H2O2 and sodium tungstate), hydrolyzed and finally decarboxylated to 2,3-dexanedione; from methyl butyl ketone and ethyl propyl ketone by way of the monoxime; also from acetoxy mesityl oxide

Taste threshold values

Taste characteristics at 50 ppm: creamy, fruity, toasted brown, caramellic notes.

General Description

Yellow liquid. Sharp penetrating odor in high concentrations. Sweet, aromatic odor when diluted.

Air & Water Reactions

Highly flammable. Insoluble in water.

Reactivity Profile

2,3-HEXANEDIONE is incompatible with strong oxidizing agents and strong bases.

Fire Hazard

2,3-HEXANEDIONE is flammable.