(4-METHOXY-BENZOYLAMINO)-ACETIC ACID
- Product Name
- (4-METHOXY-BENZOYLAMINO)-ACETIC ACID
- CAS No.
- 13214-64-7
- Chemical Name
- (4-METHOXY-BENZOYLAMINO)-ACETIC ACID
- Synonyms
- IFLAB-BB F1130-0072;4-Methoxyhippuric acid;p-Methoxyhippuric acid;(4-methoxybenzoyl)glycine;N-(4-Methoxybenzoyl)glycine;4-methyoxybenzoyl-N-glycine;Glycine, N-(4-methoxybenzoyl)-;2-(4-MethoxybenzaMido)acetic acid;(4-METHOXY-BENZOYLAMINO)-ACETIC ACID;2-[(4-METHOXYPHENYL)FORMAMIDO]ACETATE
- CBNumber
- CB2202945
- Molecular Formula
- C10H11NO4
- Formula Weight
- 209.2
- MOL File
- 13214-64-7.mol
(4-METHOXY-BENZOYLAMINO)-ACETIC ACID Property
- Melting point:
- 155-158°
- Boiling point:
- 463.7±30.0 °C(Predicted)
- Density
- 1.268±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.53±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M219185
- Product name
- 2-(4-Methoxybenzamido)AceticAcid
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- 044057
- Product name
- 2-[(4-Methoxybenzoyl)amino]acetic acid
- Purity
- >95%
- Packaging
- 500mg
- Price
- $71
- Updated
- 2021/12/16
- Product number
- AS39204
- Product name
- 2-(4-Methoxybenzamido)acetic acid
- Purity
- 97%
- Packaging
- 5G
- Price
- $302
- Updated
- 2021/12/16
- Product number
- 044057
- Product name
- 2-[(4-Methoxybenzoyl)amino]acetic acid
- Purity
- >95%
- Packaging
- 5g
- Price
- $346
- Updated
- 2021/12/16
- Product number
- CHM0019904
- Product name
- 2-[(4-METHOXYBENZOYL)AMINO]ACETIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $648.81
- Updated
- 2021/12/16
(4-METHOXY-BENZOYLAMINO)-ACETIC ACID Chemical Properties,Usage,Production
Definition
ChEBI: 2-[(4-methoxyphenyl)formamido]acetic acid is a N-acylglycine. It is functionally related to a N-benzoylglycine.
Synthesis
51220-57-6
13214-64-7
General procedure for the synthesis of 2-(4-methoxybenzoylamino)acetic acid from compound (CAS:51220-57-6): the synthesis of compound g was carried out when R1 was methoxyphenyl. The procedure was as follows: 4-methoxybenzoic acid a (2.00 g, 13.80 mmol) was added to a 200 mL round-bottomed flask with 60 mL of dichloromethane (DCM), followed by the sequential addition of EDCI (13.80 mmol), HOBt (13.80 mmol), compound b (15.77 mmol), and triethylamine (Et3N 45.99 mmol). The reaction mixture was stirred at room temperature overnight. After completion of the reaction, it was washed sequentially with water, saturated ammonium chloride solution and saturated brine and the organic phase was dried with anhydrous sodium sulfate. Purification by column chromatography with an eluent ratio of petroleum ether:ethyl acetate = 5:1 to 2:1 afforded compound c (1.80 g, 62.7% yield). Subsequently, compound c was added directly to a mixture containing 45 mL of methanol and 45 mL of aqueous sodium hydroxide (15.19 mmol) and heated to reflux for 3 hours. After completion of the reaction, the mixture was cooled to room temperature and the solvent was evaporated. After adding a small amount of water, the mixture was transferred to a beaker and the pH was adjusted to 1-2 with concentrated hydrochloric acid. extracted with ethyl acetate (EA), the organic phase was washed with saturated brine and dried over anhydrous sodium sulfate. After filtration, the solvent was evaporated to give a white solid d (1.22 g, 76.5% yield).
References
[1] Organic Letters, 2016, vol. 18, # 4, p. 696 - 699
[2] Patent: CN107216282, 2017, A. Location in patent: Paragraph 0060; 0061; 0062; 0063; 0064
(4-METHOXY-BENZOYLAMINO)-ACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
(4-METHOXY-BENZOYLAMINO)-ACETIC ACID Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 021-61317773
- Fax
- 021-61486878
- sales@aspirebio.com
- Country
- China
- ProdList
- 2880
- Advantage
- 58
- Tel
- 021-61478794
- Fax
- 021-61478794
- sales@hcshhai.com
- Country
- China
- ProdList
- 9793
- Advantage
- 50
- Tel
- 0371-88888888 272369594
- Fax
- QQ:272369594
- 2723695949@qq.com
- Country
- China
- ProdList
- 4960
- Advantage
- 50
- Tel
- 526763801 13301653310
- Fax
- +86-21-51619052
- 526763801@qq.com
- Country
- China
- ProdList
- 9273
- Advantage
- 55
- Tel
- 0-2022843681 15618226720
- Fax
- +86-21-51601218
- chaolaichem@foxmail.com
- Country
- China
- ProdList
- 12476
- Advantage
- 58
View Lastest Price from (4-METHOXY-BENZOYLAMINO)-ACETIC ACID manufacturers
- Product
- (4-METHOXY-BENZOYLAMINO)-ACETIC ACID 13214-64-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2025-05-08