Uses
ChemicalBook > CAS DataBase List > 1-ethyl-1H-indole-6-carbaldehyde

1-ethyl-1H-indole-6-carbaldehyde

Uses
Product Name
1-ethyl-1H-indole-6-carbaldehyde
CAS No.
854778-47-5
Chemical Name
1-ethyl-1H-indole-6-carbaldehyde
Synonyms
Albb-004942;1-ethyl-1H-indole-6-carbaldehyde;1H-Indole-6-carboxaldehyde, 1-ethyl-;1-ethyl-1H-indole-6-carbaldehyde(SALTDATA: FREE)
CBNumber
CB22132394
Molecular Formula
C11H11NO
Formula Weight
173.21
MOL File
854778-47-5.mol
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1-ethyl-1H-indole-6-carbaldehyde Property

Boiling point:
327.7±15.0 °C(Predicted)
Density 
1.08±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
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Safety

HazardClass 
IRRITANT
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC
Product number
B124755
Product name
1-Ethyl-1H-indole-6-carbaldehyde
Packaging
500mg
Price
$130
Updated
2021/12/16
Apolloscientific
Product number
OR929089
Product name
1-Ethyl-1H-indole-6-carbaldehyde
Purity
95%
Packaging
1g
Price
$155
Updated
2021/12/16
AK Scientific
Product number
0779AF
Product name
1-Ethyl-1H-indole-6-carbaldehyde
Packaging
1g
Price
$168
Updated
2021/12/16
Matrix Scientific
Product number
036756
Product name
1-Ethyl-1H-indole-6-carbaldehyde
Packaging
500mg
Price
$189
Updated
2021/12/16
Apolloscientific
Product number
OR929089
Product name
1-Ethyl-1H-indole-6-carbaldehyde
Purity
95%
Packaging
5g
Price
$480
Updated
2021/12/16
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1-ethyl-1H-indole-6-carbaldehyde Chemical Properties,Usage,Production

Uses

1-Ethyl-1H-indole-6-carboxaldehyde is an aldehyde derivative that can be used as a biochemical reagent.

Synthesis

1196-70-9

75-03-6

854778-47-5

GENERAL METHOD: Cesium carbonate (829 mg, 6 mmol) was added to a solution of indole-6-carboxaldehyde (435 mg, 3 mmol) in acetonitrile (30 mL) and the mixture was heated to reflux for 2 hours. Subsequently, ethyl iodide (3.3 mmol) was added to the reaction system and heating and refluxing was continued for 1 hour. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure, water was added to the residue and extracted three times with ethyl acetate. The organic layers were combined and dried with anhydrous sodium sulfate and subsequently concentrated under vacuum. Finally, the resulting residue was purified by fast column chromatography to afford the target product 1-ethyl-1H-indole-6-carbaldehyde.

References

[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 7, p. 2060 - 2079
[2] Patent: WO2014/142363, 2014, A1. Location in patent: Paragraph 0405

1-ethyl-1H-indole-6-carbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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1-ethyl-1H-indole-6-carbaldehyde Suppliers

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