ChemicalBook > CAS DataBase List > H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
- Product Name
- H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
- CAS No.
- 111857-96-6
- Chemical Name
- H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2
- Synonyms
- BIM 23042;BIM 23042 TFA;(D-2-Nal5,Cys6;BIM-23042, DC-13-217;H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2;(D-2-NAL5,CYS6·11,TYR7,D-TRP8,VAL10,2-NAL12)-SOMATOSTATIN;(D-2-NAL5,CYS6'11,TYR7,D-TRP8,VAL10,2-NAL12)-SOMATOSTATIN-14 (5-12) AMIDE;(D-2-Nal?,Cys?·??,Tyr?,D-Trp?,Val??,2-Nal??)-Somatostatin-14 (5-12) amide trifluoroacetate salt;L-Alaninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-3-(2-naphthalenyl)-, cyclic (2→7)-disulfide
- CBNumber
- CB2221348
- Molecular Formula
- C63H73N11O9S2
- Formula Weight
- 1192.45
- MOL File
- 111857-96-6.mol
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H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Property
- Boiling point:
- 1554.2±65.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- solubility
- Soluble to 1 mg/ml in 0.1% acetic acid
- form
- solid
- pka
- 9.90±0.15(Predicted)
- color
- White
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N-Bromosuccinimide Price
Usbiological
- Product number
- 254761
- Product name
- BIM 23042
- Packaging
- 1mg
- Price
- $389
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0004454
- Product name
- BIM-23042
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.93
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B5401
- Product name
- BIM23042
- Packaging
- 1mg
- Price
- $219
- Updated
- 2021/12/16
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H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Chemical Properties,Usage,Production
Biological Activity
ki: 49 ±14 nm for neuromedin b-induced endpoint in hunmbr cellsneuromedin b, a mammalian peptide of the bombesinlike peptide family sharing amino acid homology with its amphibian counterpart ranatensin, elicits a diverse array of biological responses in central and peripheral tissues. bim 23042 [d-nal-cys-tyr- d-trp-lys-val-cys-nal-nh2] is a selective neuromedin b antagonist.
in vitro
bim 23042 has a l00-fold greater affinity for bb1 receptors than bb2 receptors. the submaximal mobilisation observed with neuromedin b (1 nm) was abolished by bim 23042 but restored with a subsequently higher concentration of neuromedin b (1 μm). bim 23042 competitively inhibited neuromedin b-induced endpoint in hunmbr cells with a ki of 49 ±14 nm [1].
References
[1] ryan rr, taylor je, daniel jl, cowan a. pharmacological profiles of two bombesin analogues in cells transfected with human neuromedin b receptors. eur j pharmacol. 1996 jun 13;306(1-3):307-14.
H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 manufacturers
Henan Aochuang Chemical Co.,Ltd.
- Product
- H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2 111857-96-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-11
111857-96-6, H-D-2-NAL-CYS-TYR-D-TRP-LYS-VAL-CYS-2-NAL-NH2Related Search:
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