ChemicalBook > CAS DataBase List > 9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID

Product Name
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID
CAS No.
64072-89-5
Chemical Name
9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID
Synonyms
Δ12-PGD2;Brn 6071542;delta(sup12)-pgd2;Δ12-Prostaglandin D2;DELTA12-PROSTAGLANDIN D2;delta(sup12)-prostaglandind2;9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID;(5Z,12E,15S)-9α,15-Dihydroxy-11-oxoprosta-5,12-dien-1-oic acid;9,15-dihydroxy-11-oxo-,(5z,9-alpha,12e,15s)-prosta-12-dien-1-oicacid;(5z,9-alpha,12e,15s)-9,15-dihydroxy-11-oxoprosta-5,12-dien-1-oicacid
CBNumber
CB2223948
Molecular Formula
C20H32O5
Formula Weight
352.47
MOL File
64072-89-5.mol
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9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID Property

solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 2 mg/ml
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
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N-Bromosuccinimide Price

Cayman Chemical
Product number
12650
Product name
Δ12-Prostaglandin D2
Purity
≥98%
Packaging
500μg
Price
$51
Updated
2024/03/01
Cayman Chemical
Product number
12650
Product name
Δ12-Prostaglandin D2
Purity
≥98%
Packaging
1mg
Price
$92
Updated
2024/03/01
Cayman Chemical
Product number
12650
Product name
Δ12-Prostaglandin D2
Purity
≥98%
Packaging
5mg
Price
$434
Updated
2024/03/01
Cayman Chemical
Product number
12650
Product name
Δ12-Prostaglandin D2
Purity
≥98%
Packaging
10mg
Price
$765
Updated
2024/03/01
Medical Isotopes, Inc.
Product number
D18825
Product name
Δ12-Prostaglandin-d2
Purity
>98%
Packaging
0.5mg
Price
$790
Updated
2021/12/16
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9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID Chemical Properties,Usage,Production

Description

Prostaglandin D2 (PGD2) is one of the five primary enzymatic prostaglandins derived directly from PGH2. PGD2 is produced abundantly in the CSF by the lipocalin-type PGD synthase, and in the periphery by myeloid cells including mast cells and basophils by a second, hematopoietic-type PGD synthase. PGD2 is chemically unstable, and its use and analysis is complicated by its short in vivo half-life. Δ12-PGD2 is one of the initial chemical decomposition products of PGD2. Δ12-PGD2 is an intermediate in the pathway leading to Δ12-PGJ2, which is a cyclopentenone prostaglandin with antimitotic and carcinogenic activities. The metabolism of Δ12-PGD2 involves addition of thiol nucleophiles, as is the case with the majority of cyclopentenone prostaglandins.

Uses

Δ12(E)-Prostaglandin D2 is a derivative of Prostaglandin D2 (HY-101988). Prostaglandin D2 is one of the major Prostaglandins actively produced in the brain of various mammals[1].

References

[1] J Atsmon, et al. Formation of thiol conjugates of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 and delta 12(E)-prostaglandin D2. Biochemistry. 1990 Apr 17;29(15):3760-5. DOI:10.1021/bi00467a023

9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID Suppliers

Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
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China
ProdList
6777
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
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58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11973
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58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29423
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Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
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58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
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58
Guangzhou Biopark Technology Co., Ltd.
Tel
020-83808789
Country
CHINA
ProdList
179
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58

64072-89-5, 9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACIDRelated Search:


  • DELTA12-PROSTAGLANDIN D2
  • 9ALPHA,15S-DIHYDROXY-11-OXO-PROSTA-5Z,12E-DIEN-1-OIC ACID
  • (5z,9-alpha,12e,15s)-9,15-dihydroxy-11-oxoprosta-5,12-dien-1-oicacid
  • 9,15-dihydroxy-11-oxo-,(5z,9-alpha,12e,15s)-prosta-12-dien-1-oicacid
  • delta(sup12)-pgd2
  • delta(sup12)-prostaglandind2
  • (5Z,12E,15S)-9α,15-Dihydroxy-11-oxoprosta-5,12-dien-1-oic acid
  • Δ12-PGD2
  • Δ12-Prostaglandin D2
  • Brn 6071542
  • Prosta-5,12-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9-alpha,12E,15S)-
  • Prosta-5,12-dien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,12E,15S)-
  • 64072-89-5