1-(Prop-2-yn-1-yl)pyrrolidine

Product Name: 1-(Prop-2-yn-1-yl)pyrrolidine
CAS No.: 5799-76-8
Chemical Name: 1-(Prop-2-yn-1-yl)pyrrolidine
Synonyms: RMA-92;4-PropargylMorpholine;1-Morpholino-2-propyne;4-(prop-2-ynyl)Morpholine;1-(N-Morpholino)-2-propyne;4-PROP-2-YN-1-YLMORPHOLINE;Morpholine, 4-(2-propynyl)-;3-(4-morpholinyl)-1-propyne;3-(N-Morpholinyl)-1-Propyne;1-PROP-2-YN-1-YLPYRROLIDINE
CBNumber: CB22448240
Molecular Formula: C7H11NO
Formula Weight: 125.17
MOL File: 5799-76-8.mol

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1-(Prop-2-yn-1-yl)pyrrolidine Property

Boiling point:: 186°C(lit.)
Density: 1.0009 g/cm3
refractive index: 1.4730 to 1.4770
storage temp.: 2-8°C
form: clear liquid
pka: 5.14±0.10(Predicted)
color: Colorless to Light yellow
InChI: InChI=1S/C7H11NO/c1-2-3-8-4-6-9-7-5-8/h1H,3-7H2
InChIKey: OKDZHAQIKCVKFE-UHFFFAOYSA-N
SMILES: N1(CC#C)CCOCC1

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Safety

RIDADR: UN 1993 3/PG III
HazardClass: 3
PackingGroup: III
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

TCI Chemical

Product number: P2170
Product name: 4-(2-Propyn-1-yl)morpholine
Purity: >98.0%(GC)
Packaging: 200mg
Price: $105
Updated: 2025/07/31

TCI Chemical

Product number: P2170
Product name: 4-(2-Propyn-1-yl)morpholine
Purity: >98.0%(GC)
Packaging: 1g
Price: $304
Updated: 2025/07/31

TRC

Product number: P838593
Product name: 4-(Prop-2-yn-1-yl)morpholine
Packaging: 500mg
Price: $200
Updated: 2021/12/16

Activate Scientific

Product number: AS26940
Product name: 1-Morpholino-2-propyne
Purity: 97+%
Packaging: 5G
Price: $131
Updated: 2021/12/16

Activate Scientific

Product number: AS26940
Product name: 1-Morpholino-2-propyne
Purity: 97+%
Packaging: 25g
Price: $426
Updated: 2021/12/16

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1-(Prop-2-yn-1-yl)pyrrolidine Chemical Properties,Usage,Production

Uses

1-(Prop-2-yn-1-yl)pyrrolidine is used as an intermediate in organic synthesis or pharmaceuticals.

Synthesis

110-91-8

106-96-7

5799-76-8

The general procedure for the synthesis of 1-(4-morpholinyl)-2-propyne from morpholine and 3-bromopropargyl was as follows: morpholine (100 mL, 1.148 mol) was dissolved in methanol (1 L) and cooled in an ice bath under nitrogen protection. Subsequently, potassium carbonate (120 g, 0.63 mol) and propargyl bromide (124 mL, 1.148 mol) were sequentially added under ice bath stirring conditions. The reaction mixture was continued to be stirred without cooling for 4 hours. After completion of the reaction, the resulting white suspension was filtered through filter paper and the solid residue was washed with methanol (100 mL). The filtrates were combined and methanol was removed by careful evaporation. The white precipitate obtained was suspended in dichloromethane (400 mL), filtered again through filter paper and the solvent was carefully evaporated. Finally, the product was distilled under reduced pressure at 60 °C and 16 mbar to give 100 g of colorless oily product in 70% yield.

References

[1] Journal of Organometallic Chemistry, 1983, vol. 244, # 4, p. 311 - 318
[2] Journal of Combinatorial Chemistry, 2010, vol. 12, # 4, p. 491 - 496
[3] Journal of the American Chemical Society, 2014, vol. 136, # 12, p. 4740 - 4745
[4] Green Chemistry, 2009, vol. 11, # 8, p. 1115 - 1120
[5] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1982, p. 1459 - 1466

1-(Prop-2-yn-1-yl)pyrrolidine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(Prop-2-yn-1-yl)pyrrolidine Suppliers

China 98 India 4 Japan 1 United Kingdom 2 United States 5 Global 110

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View Lastest Price from 1-(Prop-2-yn-1-yl)pyrrolidine manufacturers

Career Henan Chemical Co

Product: 1-PROP-2-YN-1-YLPYRROLIDINE 5799-76-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000KG
Release date: 2019-09-04

5799-76-8, 1-(Prop-2-yn-1-yl)pyrrolidineRelated Search:

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1-PROP-2-YN-1-YLPYRROLIDINE

3-(N-Morpholinyl)-1-Propyne

1-Morpholino-2-propyne

3-(4-morpholinyl)-1-propyne

4-(prop-2-ynyl)Morpholine

1-(N-Morpholino)-2-propyne

4-PropargylMorpholine

Morpholine, 4-(2-propynyl)-

Morpholine, 4-(2-propyn-1-yl)-

4-PROP-2-YN-1-YLMORPHOLINE

RMA-92

5799-76-8