ChemicalBook > CAS DataBase List > 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE

Product Name
2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE
CAS No.
865758-95-8
Chemical Name
2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE
Synonyms
Alogliptin 6-Chloro N-Desmethyl Impurity;Alogliptin-5;ALOGLIPTIN int2;Alogliptin Impurity 08;alogliptin impurities10;alogliptin impurities157;Alogliptin Related Compound 27;Agger coluMn dean interMediates;Benzonitrile, 2-[(6-chloro-3,4-dihydro-2,4-dioxo-1(2H)-pyrim...;2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile
CBNumber
CB22452423
Molecular Formula
C12H8ClN3O2
Formula Weight
261.66
MOL File
865758-95-8.mol
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2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE Property

Density 
1.48
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Dichloromethane, Ethyl Acetate, Methanol
form 
Solid
pka
8.11±0.40(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C365465
Product name
2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile
Packaging
250mg
Price
$1320
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0356880
Product name
2-((6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL)BENZONITRILE
Purity
95.00%
Packaging
5MG
Price
$501.02
Updated
2021/12/16
ChemScene
Product number
CS-M2294
Product name
2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile
Packaging
50mg
Price
$141
Updated
2021/12/16
ChemScene
Product number
CS-M2294
Product name
2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile
Packaging
100mg
Price
$234
Updated
2021/12/16
Crysdot
Product number
CD11041261
Product name
2-((6-Chloro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)benzonitrile
Purity
95+%
Packaging
100mg
Price
$277
Updated
2021/12/16
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2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Alogliptin (A575425) intermediate.

Uses

2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile is used as a reactant/ intermediate in discovery of Alogliptin (A575425), which is an antidiabetic agent.

2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE Suppliers

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View Lastest Price from 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
Agger coluMn dean interMediates 865758-95-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2024-11-13
Career Henan Chemical Co
Product
2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE 865758-95-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-09

865758-95-8, 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILERelated Search:

Alogliptin Impurity B 2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile 2-(AMinoMethyl)benzonitrile hydrochloride Alogliptin benzoate impurity K Benzonitrile, 2-[(tetrahydro-3-Methyl-2,4,6-trioxo-1(2H)-pyriMidinyl)Methyl]- Alogliptin Related Compound 26 α,α-Dibromo-o-tolunitrile 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE (R)-2-((3-methyl-2,4-dioxo-6-(piperidin-3-ylamino)-3,4-Dihydro- pyrimidin-1(2H)-yl)methyl)benzonitrile hydrogen chloride Alogliptin Related Compound 18 Alogliptin Impurity 34 Alogliptin Related Compound 32 Alogliptin Impurity 35 Alogliptin Related Compound 21 (R)-2-((6-(3-((3-(2-cyanobenzyl)-1-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyriMidin-4-yl)aMino)piperidin-1-yl)-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)benzonitrile Alogliptin Impurity 16 Alogliptin Impurity 10 Alogliptin Related Compound 31

  • 2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE
  • 2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile
  • 2-[(6-Chloro-3,4-dihydro-2,4-dioxo-1(2H)-pyriMidinyl)Methyl]-benzonitrile
  • Agger coluMn dean interMediates
  • Benzonitrile, 2-[(6-chloro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-
  • Alogliptin Related Compound 27
  • ALOGLIPTIN int2
  • Alogliptin-5
  • Alogliptin impurity 9/2-((6-Chloro-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)methyl)benzonitrile
  • Alogliptin 6-Chloro N-Desmethyl Impurity
  • Benzonitrile, 2-[(6-chloro-3,4-dihydro-2,4-dioxo-1(2H)-pyrim...
  • alogliptin impurities157
  • alogliptin impurities10
  • Alogliptin Impurity 08
  • 865758-95-8
  • 895758-95-8