ChemicalBook > CAS DataBase List > 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
- Product Name
- 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
- CAS No.
- 157066-76-7
- Chemical Name
- 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
- Synonyms
- SNAP 5089;3-Pyridinecarboxylic acid, 5-[[[3-(4,4-diphenyl-1-piperidinyl)propyl]amino]carbonyl]-1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)-, methyl ester;5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
- CBNumber
- CB22453420
- Molecular Formula
- C36H40N4O5
- Formula Weight
- 608.73
- MOL File
- 157066-76-7.mol
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5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE Property
- Boiling point:
- 780.3±60.0 °C(Predicted)
- Density
- 1.198±0.06 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- <64.52mg/ml in DMSO; <64.52mg/ml in ethanol
- pka
- 14.77±0.70(Predicted)
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N-Bromosuccinimide Price
Usbiological
- Product number
- 256707
- Product name
- SNAP 5089
- Packaging
- 10mg
- Price
- $403
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- BRS0000753
- Product name
- 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.99
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7040
- Product name
- SNAP5089
- Packaging
- 50mg
- Price
- $1017
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B7040
- Product name
- SNAP5089
- Packaging
- 10mg
- Price
- $242
- Updated
- 2021/12/16
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5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
SNAP 5089 is an a1c adrenergic receptor antagonist.
Biological Activity
Subtype-selective α 1A -adrenoceptor antagonist that displays > 600-fold selectivity over other adrenoceptors (K i values are 0.35, 220, 370, 540, 800 and 1200 nM for α 1A , α 1B , α 2C , α 1D , α 2B and α 2A subtypes respectively and 540 nM for L-type Ca 2+ channels). Inhibits noradrenalin-induced contractions in rabbit vascular and lower urinary tissues.
5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE Suppliers
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157066-76-7, 5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDERelated Search:
4-N-Methylbenzyl-N-carbethoxypiperidine dihydrochloride
4,4-DIPHENYLPIPERIDINE HYDROCHLORIDE
5-[[[3-(4,4-DIPHENYL-1-PIPERIDINYL)PROPYL]AMINO]CARBONYL]-1,4-DIHYDRO-2,6-DIMETHYL-4-(4-NITROPHENYL)-3-PYRIDINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE