ChemicalBook > CAS DataBase List > 1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE

1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE

Product Name
1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE
CAS No.
942185-01-5
Chemical Name
1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE
Synonyms
5-AMino-1H-pyrazolo[3,4-b...;1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE;5-AMino-1H-pyrazolo[3,4-b]pyridine;1H-Pyrazolo[3,4-b]pyridin-5-ylamine;1H-Pyrazolo[3,4-b]pyridin-6-ylamine HCl;1H-Pyrazolo[3,4-b]pyridin-5-ylamine HCl
CBNumber
CB22454856
Molecular Formula
C6H6N4
Formula Weight
134.14
MOL File
942185-01-5.mol
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1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE Property

Boiling point:
388.3±22.0 °C(Predicted)
Density 
1.480±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
10.43±0.40(Predicted)
Appearance
Light yellow to brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B529853
Product name
1H-Pyrazolo[3,4-b]pyridin-5-amine
Packaging
50mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-1-AL
Product name
5-Amino-1H-pyrazolo[3,4-b]pyridine
Packaging
250mg
Price
$175
Updated
2021/12/16
AK Scientific
Product number
Y5668
Product name
1H-Pyrazolo[3,4-b]pyridin-5-amine
Packaging
1g
Price
$177
Updated
2021/12/16
AK Scientific
Product number
Y5668
Product name
1H-Pyrazolo[3,4-b]pyridin-5-amine
Packaging
5g
Price
$474
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0387120
Product name
1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE
Purity
95.00%
Packaging
5MG
Price
$496.02
Updated
2021/12/16
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1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE Chemical Properties,Usage,Production

Synthesis

63572-73-6

942185-01-5

General procedure for the synthesis of 1H-pyrazolo[3,4-b]pyridin-5-amine from 5-nitro-7-azaindazole: 5-nitro-1H-pyrazolo[3,4-b]pyridine (308 mg, 1.876 mmol) was dissolved in a mixed solvent of ethanol and tetrahydrofuran, and 10% palladium-carbon-catalyst (40 mg) was added. The reaction mixture was stirred for 15 hours under hydrogen atmosphere. After completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the filtrate was purified by column chromatography to afford the target product 1H-pyrazolo[3,4-b]pyridin-5-amine (73 mg) in 89% yield.

References

[1] Patent: WO2013/13816, 2013, A1. Location in patent: Page/Page column 73; 74
[2] Patent: US2013/29995, 2013, A1. Location in patent: Paragraph 0374-0375
[3] European Journal of Medicinal Chemistry, 2017, vol. 131, p. 1 - 13
[4] Patent: WO2007/70398, 2007, A1. Location in patent: Page/Page column 249

1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE Suppliers

China 64 India 2 United States 4 Global 70
ZEROSCHEM.CO.,LTD.
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10-61256048 13810278579
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+86 10 61256049
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sales@zeroschem.com
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China
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QINGDAO CARELONGPHARMATECH CO.,LTD
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0532-0532-88191853 13061484198
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+86-532-88191853
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sales@carelongchem.com
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China
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Chiba Pharmaceutical Science and technology Co, Ltd.
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0531-81313138 13066006660
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QQ: 3366077777
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chibapharm@foxmail.com
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China
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CEG Chemical Science&Technology Co., Ltd.
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Mobile:13665161512
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+86-510-68873513
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China
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Shanghai Carlow Chemicals Co., Ltd.
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21-33526724 18930996265
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37023730
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info@carlowchem.com
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Hubei XinyuanShun Chemical Co., Ltd.
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hbeixys2001@163.com
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Nanjing YiFan Biological Technology Co., Ltd.
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025-025-52700520 18914499889
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China
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Cool Pharm, Ltd
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021-60455363 18019463053
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50966098
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sales@coolpharm.com
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China
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Hangzhou Milestone Pharmtech Co., Ltd.
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0571-82896630 18969958410
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sales_hz@milestonepharmtech.com
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China
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Shanghai Boyners Pharm-Tech Co., Ltd.
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13817873692
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021-31329586
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mkt@boynerspharm.com
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China
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View Lastest Price from 1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE manufacturers

Career Henan Chemical Co
Product
1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE 942185-01-5
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg -1000kg
Release date
2020-01-02

942185-01-5, 1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINERelated Search:

N-(4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-5-YL)-N'-[1-(4-CHLOROPHENYL)-1-METHYL-1-OXO-LAMBDA6-SULFANYLIDENE]UREA N-(pentan-3-yl)-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine N-(4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-5-YL)-N'-[3,5-DI(TRIFLUOROMETHYL)PHENYL]UREA N-(4-CHLORO-1,3-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-5-YL)-N'-(2-CHLOROPHENYL)UREA 1-Isopropyl-1H-pyrazolo[3,4-b]pyridin-5-aMine;1-(1-Methylethyl)-1H-pyrazolo[3,4-b]pyridin-5-aMine N-(2-methylpropyl)-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine N-cyclopentyl-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine N-(3-methylbutyl)-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine 1-(propan-2-yl)-N-(thiolan-3-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine N-pentyl-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine 1,3-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE N-(1-cyclopropylethyl)-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine N-(1H-pyrazolo[3,4-b]pyridin-5-yl)thiourea N-(2-methylbutyl)-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine N-(pentan-2-yl)-1-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridin-5-amine 1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE

  • 1H-PYRAZOLO[3,4-B]PYRIDIN-5-AMINE
  • 1H-Pyrazolo[3,4-b]pyridin-5-ylamine
  • 5-AMino-1H-pyrazolo[3,4-b...
  • 5-AMino-1H-pyrazolo[3,4-b]pyridine
  • 1H-Pyrazolo[3,4-b]pyridin-5-ylamine HCl
  • 1H-Pyrazolo[3,4-b]pyridin-6-ylamine HCl
  • 942185-01-5