4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE
- Product Name
- 4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE
- CAS No.
- 10235-65-1
- Chemical Name
- 4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE
- Synonyms
- 4,6-Dichloro-2-(pyridin-2-yl);4,6-Dichloro-2-(2-pyridyl)pyrimidine;4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE;Pyrimidine, 4,6-dichloro-2-(2-pyridinyl)-
- CBNumber
- CB22458531
- Molecular Formula
- C9H5Cl2N3
- Formula Weight
- 226.06
- MOL File
- 10235-65-1.mol
4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE Property
- Boiling point:
- 254.5±22.0 °C(Predicted)
- Density
- 1.428±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -0.57±0.19(Predicted)
- Appearance
- White to light brown Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D437383
- Product name
- 4,6-Dichloro-2-(2-pyridinyl)pyrimidine
- Packaging
- 500mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- FD142218
- Product name
- 4,6-Dichloro-2-(pyridin-2-yl)pyrimidine
- Packaging
- 100mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FD142218
- Product name
- 4,6-Dichloro-2-(pyridin-2-yl)pyrimidine
- Packaging
- 250mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- Z3810
- Product name
- 4,6-Dichloro-2-(2-pyridinyl)pyrimidine
- Packaging
- 100mg
- Price
- $142
- Updated
- 2021/12/16
- Product number
- FD142218
- Product name
- 4,6-Dichloro-2-(pyridin-2-yl)pyrimidine
- Packaging
- 500mg
- Price
- $240
- Updated
- 2021/12/16
4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE Chemical Properties,Usage,Production
Synthesis
10198-74-0
10235-65-1
B) To a 25 mL round bottom flask were sequentially added 6-hydroxy-2-(pyridin-2-yl)pyrimidin-4(5H)-one (1 g, 5.29 mmol), phosphorus trichloride (4.82 mL, 52.9 mmol) and phosphorus pentachloride (1.10 g, 5.29 mmol). The reaction mixture was heated to 106 °C and refluxed overnight. After the reaction was completed, the solvent was removed by evaporation. The pH of the reaction mixture was adjusted to 7-8 with saturated sodium bicarbonate solution. the aqueous phase was extracted with ethyl acetate (40 mL × 2) and the organic layers were combined. The organic layer was washed sequentially with 80 mL of water and 80 mL of saturated saline, and then dried over anhydrous sodium sulfate. The dried organic phase was concentrated and the resulting residue was quickly purified by silica gel column chromatography with the eluent of petroleum ether/ethyl acetate (V/V = 8:1). 4,6-Dichloro-2-[2-pyridyl]pyrimidine (0.96 g, white solid) was finally obtained in 80% yield.
References
[1] Patent: CN106608869, 2017, A. Location in patent: Paragraph 0104; 0105; 0107
[2] Patent: US2012/202806, 2012, A1
[3] Patent: US6372751, 2002, B1. Location in patent: Example Pr3
4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE manufacturers
- Product
- 4,6-Dichloro-2-(2-pyridinyl)pyriMidine 10235-65-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2020-05-15
- Product
- 4,6-DICHLORO-2-(2-PYRIDINYL)PYRIMIDINE 10235-65-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-02