(2-AMINO-4-PYRIDYL)BORONIC ACID
- Product Name
- (2-AMINO-4-PYRIDYL)BORONIC ACID
- CAS No.
- 903513-62-2
- Chemical Name
- (2-AMINO-4-PYRIDYL)BORONIC ACID
- Synonyms
- (2-Aminopyridin-4-yl);(2-AMINO-4-PYRIDYL)BORONIC;2-Aminopyridine-4-boronic acid;(2-Aminopyridin-4-yl)boronicaci;2-aminopyridin-4-ylboronic acid;(2-AMINO-4-PYRIDYL)BORONIC ACID;2-aMino-4-pyridinyl boronic acid;Boronic acid, B-(2-amino-4-pyridinyl)-;(2-AMINO-4-PYRIDYL)BORONIC ACID ISO 9001:2015 REACH
- CBNumber
- CB22459149
- Molecular Formula
- C5H7BN2O2
- Formula Weight
- 137.93
- MOL File
- 903513-62-2.mol
(2-AMINO-4-PYRIDYL)BORONIC ACID Property
- Boiling point:
- 411.7±55.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
- pka
- 5.74±0.10(Predicted)
- Appearance
- Off-white to gray Solid
N-Bromosuccinimide Price
- Product number
- A632583
- Product name
- (2-Amino-4-pyridyl)boronicAcid
- Packaging
- 25mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- CS-W005555
- Product name
- (2-Aminopyridin-4-yl)boronicacid
- Packaging
- 250mg
- Price
- $169
- Updated
- 2021/12/16
- Product number
- 118454
- Product name
- (2-Aminopyridin-4-yl)boronic acid
- Packaging
- 500mg
- Price
- $247
- Updated
- 2021/12/16
- Product number
- FA76337
- Product name
- (2-Aminopyridin-4-yl)boronic acid
- Packaging
- 50mg
- Price
- $300
- Updated
- 2021/12/16
- Product number
- 118454
- Product name
- (2-Aminopyridin-4-yl)boronic acid
- Packaging
- 1g
- Price
- $380
- Updated
- 2021/12/16
(2-AMINO-4-PYRIDYL)BORONIC ACID Chemical Properties,Usage,Production
Synthesis
19798-80-2
903513-62-2
General procedure for the synthesis of (2-aminopyridin-4-yl)boronic acid from 2-amino-4-chloropyridine: 2-amino-4-chloropyridine (3 g, 23.34 mmol), bis(pinacolato)diboron (17.78 g, 70.1 mmol), 2-dicyclohexylphosphino-2',6'-dimethoxybiphenyl (0.38 g, 0.93 mmol), tris( dibenzylideneacetone) dipalladium(0) (0.21 g, 0.23 mmol) and potassium acetate (3.89 g, 39.67 mmol) were mixed in 1,4-dioxane (78 mL) under nitrogen atmosphere. The reaction mixture was stirred at 100 °C for 3 hours. Upon completion of the reaction, the hot reaction mixture was filtered through diatomaceous earth and washed with ethyl acetate (EtOAc). The organic layer was concentrated under vacuum and the residue was precipitated with diisopropyl ether (DIPE) to afford the intermediate compound 1-24 ((2-aminopyridin-4-yl)boronic acid) as a white solid (5.84 g, quantitative yield), which could be used in the next reaction without further purification.
References
[1] Patent: WO2014/195311, 2014, A1. Location in patent: Page/Page column 88
[2] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 7, p. 1879 - 1882
(2-AMINO-4-PYRIDYL)BORONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (2-AMINO-4-PYRIDYL)BORONIC ACID manufacturers
- Product
- (2-AMINO-4-PYRIDYL)BORONIC ACID 903513-62-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-04-30
- Product
- (2-AMINO-4-PYRIDYL)BORONIC ACID 903513-62-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-100%
- Supply Ability
- 1
- Release date
- 2018-08-12