1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)-

Product Name: 1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)-
CAS No.: 915226-43-6
Chemical Name: 1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)-
Synonyms: (R)-1-Boc-3-carbamoylpiperidine;(R)-1-Boc-3-piperidinecarboxaMide;(R)-1-Boc-3-(aMinocarbonyl)-piperidine;tert-Butyl (R)-3-carbamoylpiperidine-1-carboxylate;(R)-tert-Butyl 3-carbaMoylpiperidine-1-carboxylate;tert-butyl (3R)-3-carbamoylpiperidine-1-carboxylate;1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)-
CBNumber: CB22468655
Molecular Formula: C11H20N2O3
Formula Weight: 228.29
MOL File: 915226-43-6.mol

More

Less

1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)- Property

Boiling point:: 384.4±31.0 °C(Predicted)
Density: 1.123±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 16.41±0.20(Predicted)
Appearance: White to off-white Solid
optical activity: Consistent with structure

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Activate Scientific

Product number: AS43276
Product name: (R)-tert-Butyl 3-carbamoylpiperidine-1-carboxylate
Purity: 95% ee
Packaging: 250mg
Price: $72
Updated: 2021/12/16

Activate Scientific

Product number: AS43276
Product name: (R)-tert-Butyl 3-carbamoylpiperidine-1-carboxylate
Purity: 95% ee
Packaging: 1g
Price: $122
Updated: 2021/12/16

AK Scientific

Product number: 5386AC
Product name: (R)-tert-Butyl3-carbamoylpiperidine-1-carboxylate
Packaging: 1g
Price: $154
Updated: 2021/12/16

Activate Scientific

Product number: AS43276
Product name: (R)-tert-Butyl 3-carbamoylpiperidine-1-carboxylate
Purity: 95% ee
Packaging: 5G
Price: $342
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CCH0033088
Product name: (R)-TERT-BUTYL-3-CARBAMOYLPIPERIDINE-1-CARBOXYLATE
Purity: 95.00%
Packaging: 250MG
Price: $342.3
Updated: 2021/12/16

More

Less

1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)- Chemical Properties,Usage,Production

Synthesis

4138-26-5

24424-99-5

915226-43-6

The general procedure for the synthesis of tert-butyl (R)-3-carbamoylpiperidine-1-carboxylate from 3-piperidinecarboxamide and di-tert-butyl dicarbonate was as follows: to the reaction mixture obtained in Example 4 was added tetrahydrofuran (THF, 40 mL), followed by the addition of di-tert-butyl dicarbonate (37.2 g, 2.3 eq.). The pH of the reaction mixture was adjusted to 10.0 using sodium hydroxide (NaOH). the reaction mixture was stirred at room temperature for 1 hr, after which the precipitated crystals were collected by filtration to afford (R)-1 -(tert-butoxycarbonyl)piperidinamide as white crystals (15.6 g, yield: 93%). The crystals were analyzed using the method described in Example 3; the results showed an optical purity of 99.8% ee. 1H NMR (400 MHz, CDCl3) data were as follows: δ 5.36 (brs, 2H), 3.94-3.08 (m, 5H), 1.96-1.36 (m, 13H).

References

[1] Patent: US2010/105917, 2010, A1. Location in patent: Page/Page column 16

1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)- Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)- Suppliers

China 30 India 1 United States 3 Global 34

ForeChem (Nantong) Technology Co.,Ltd.

Tel: 513-85982855 18921614129
Fax: 051385915507
Email: sales@xianxingpharm.com
Country: China
ProdList: 2986
Advantage: 61

AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: 15928766785 15928766785
Fax: QQ961458712
Email: wupengcheng@astatech.cn
Country: China
ProdList: 1987
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Chengdu Firster Pharmaceutical Co., Ltd.

Tel: 028-87078428 028-87074958
Fax: 8772-8116
Email: chengzhenyong@cdfirster.com
Country: China
ProdList: 2598
Advantage: 60

Chengdu Chuangkecheng Biological Technology Co., Ltd.

Tel: 028-028-0000000 13008177686
Fax: 15928581901
Email: sales@ckcbiotech.com
Country: China
ProdList: 904
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Blocksynth Pharmaceutical Technology Co.,Ltd

Tel: 0086-19817745290; +8619817745290
Email: bd@blocksynth.com
Country: China
ProdList: 5661
Advantage: 58

Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd.

Tel: 15990591583
Fax: qq: 1050376806 mailbox : sales@nbpharmabridge.com
Country: China
ProdList: 6108
Advantage: 58

Guizhou Yituo Chemical Technology Co., Ltd

Tel: 18628235590
Fax: QQ:444176500
Email: wuliming@yituochem.cn
Country: China
ProdList: 1242
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Chengdu Jiuding Chemical Technology Co., Ltd. - Song Bo

Tel: 18584079237
Email: 312074905@qq.com
Country: China
ProdList: 2513
Advantage: 58

Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
Advantage: 58

Shandong WorldSun Biological Technology Co., Ltd.

Tel: 0531-88723173 18596073690
Email: 1047208234@qq.com
Country: China
ProdList: 6780
Advantage: 58

Shandong Territorial sea Biological Technology Co., LTD

Tel: 15092083467
Email: 18660263263@163.com
Country: China
ProdList: 2811
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Nanjing Wogni Chemical Co., Ltd.

Tel: 15996452985
Email: foxerhy@163.com
Country: China
ProdList: 4939
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169109
Email: market03@meryer.com
Country: China
ProdList: 27987
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50751
Advantage: 58

Lianhe Aigen Pharmatech Co.,Ltd.

Tel: 18918657159
Email: sales-Aigen@lianhetech.com
Country: China
ProdList: 3000
Advantage: 58

Ningbo Zhenyue Pharmaceutical Technology Co., Ltd

Tel: 19817745290
Email: bd@blocksynth.com
Country: China
ProdList: 5870
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: 400-6206333 13167063860
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 48457
Advantage: 58

BEIJINGYIWANJINGRUI

Tel: 15866847540
Email: dengyt2000@163.com
Country: China
ProdList: 4100
Advantage: 58

Hubei Moco Chemical Co., Ltd.

Tel: 18627753421; 18627756402
Fax: QQ：3001051413
Email: 3001051413@qq.com
Country: China
ProdList: 20319
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 14580
Advantage: 58

Guangzhou Zhenhao Biotechnology Co., Ltd.

Tel: 13430395027
Country: CHINA
ProdList: 115
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

915226-43-6, 1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)-Related Search:

1-PIPERIDINECARBOXYLIC ACID, 3-(AMINOCARBONYL)-, 1,1-DIMETHYLETHYL ESTER, (3R)-

(R)-1-Boc-3-piperidinecarboxaMide

(R)-1-Boc-3-(aMinocarbonyl)-piperidine

(R)-tert-Butyl 3-carbaMoylpiperidine-1-carboxylate

tert-Butyl (R)-3-carbamoylpiperidine-1-carboxylate

(R)-1-Boc-3-carbamoylpiperidine

tert-butyl (3R)-3-carbamoylpiperidine-1-carboxylate

915226-43-6