ChemicalBook > CAS DataBase List > 2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE

2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE

Product Name
2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE
CAS No.
960289-03-6
Chemical Name
2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE
Synonyms
2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H);2-broMo-4H,5H,6H,7H-thieno[2,3-c]pyridin-7-one;2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE;2-broMo-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one;Thieno[2,3-c]pyridin-7(4H)-one, 2-bromo-5,6-dihydro-;2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4h)-oneone;2-Bromo-7-oxo-4,5,6,7-tetrahydrothieno[2,3-c]pyridine;2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)-one,tech
CBNumber
CB22468998
Molecular Formula
C7H6BrNOS
Formula Weight
232.1
MOL File
960289-03-6.mol
More
Less

2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE Property

Boiling point:
471.8±45.0 °C(Predicted)
Density 
1.726±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
13.97±0.20(Predicted)
Appearance
White to off-white Solid
More
Less

Safety

HS Code 
2934999090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More
Less

N-Bromosuccinimide Price

TRC
Product number
B691428
Product name
2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)-one
Packaging
25mg
Price
$170
Updated
2021/12/16
AK Scientific
Product number
Y5686
Product name
2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)-one
Packaging
100mg
Price
$210
Updated
2021/12/16
SynQuest Laboratories
Product number
8H70-9-Y3
Product name
2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)-one
Packaging
250mg
Price
$496
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0363217
Product name
2-BROMO-5,6-DIHYDROTHIENO-[2,3-C]PYRIDIN-7(4H)-ONE
Purity
95.00%
Packaging
5MG
Price
$505.99
Updated
2021/12/16
SynQuest Laboratories
Product number
8H70-9-Y3
Product name
2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)-one
Packaging
1g
Price
$1376
Updated
2021/12/16
More
Less

2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE Chemical Properties,Usage,Production

Uses

2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)-one is an intermediate in preparation of thieno[2,3-c]pyridine derivatives as MCH receptor antagonists.

Synthesis

14470-51-0

960289-03-6

General procedure for the synthesis of 2-bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)-ones from 5,6-dihydrothieno[2,3-c]pyridin-7(4H)-ones: 5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one (4.80 g, 31.37 mmol) was dissolved in acetic acid (40 mL) and water (30 mL ) in a solvent mixture. After cooling the reaction mixture to 0°C, bromine (1.8 mL, 34.51 mmol) was added slowly and dropwise. The reaction was continuously stirred at 0°C for 1 hour. After completion of the reaction, the reaction mixture was diluted with 100 mL of water and extracted with ethyl acetate (3 x 100 mL). The organic layers were combined, washed sequentially with 5% sodium sulfite solution (2 × 50 mL) and saturated sodium bicarbonate solution (2 × 100 mL), dried over anhydrous sodium sulfate, filtered and concentrated to afford 6.20 g (85% yield) of the target product 2-bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)-one. Mass spectral analysis (MS/ESI) m/z (81Br) 233.9 [M+H]+.

References

[1] Patent: WO2007/146759, 2007, A2. Location in patent: Page/Page column 26
[2] Patent: WO2007/146758, 2007, A2. Location in patent: Page/Page column 34
[3] Patent: US2012/225857, 2012, A1. Location in patent: Page/Page column 16

2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE Suppliers

China 33 Germany 1 India 1 United Kingdom 2 United States 7 Global 44
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United Kingdom
ProdList
6401
Advantage
74

960289-03-6, 2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONERelated Search:

Deltamethrin

  • 2-BROMO-5,6-DIHYDROTHIENO[2,3-C]PYRIDIN-7(4H)-ONE
  • 2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)
  • 2-Bromo-7-oxo-4,5,6,7-tetrahydrothieno[2,3-c]pyridine
  • 2-broMo-4H,5H,6H,7H-thieno[2,3-c]pyridin-7-one
  • 2-broMo-5,6-dihydro-4H-thieno[2,3-c]pyridin-7-one
  • 2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4H)-one,tech
  • 2-Bromo-5,6-dihydrothieno[2,3-c]pyridin-7(4h)-oneone
  • Thieno[2,3-c]pyridin-7(4H)-one, 2-bromo-5,6-dihydro-
  • 960289-03-6
  • C7H6BrNOS