5-Iodo-2,3-dihydropyridazin-3-one
- Product Name
- 5-Iodo-2,3-dihydropyridazin-3-one
- CAS No.
- 825633-94-1
- Chemical Name
- 5-Iodo-2,3-dihydropyridazin-3-one
- Synonyms
- 5-Iodopyridazin-3(2H)-one;5-lodopyridazin-3(2H)-one;5-Iodo-2H-pyridazin-3-one;5-Iodo-3(2H)-pyridazinone;3(2H)-Pyridazinone, 5-iodo-;5-Iodo-3(2H)-pyridazinone, 95+%;5-Iodo-3(2H)-pyridazinone;5-Iodo-2,3-dihydropyridazin-3-on;5-Iodo-2,3-dihydropyridazin-3-one;5-I0D0-2,3- DIHYDR0PYRIDAZIN-3-0NE
- CBNumber
- CB22470935
- Molecular Formula
- C4H3IN2O
- Formula Weight
- 221.98
- MOL File
- 825633-94-1.mol
5-Iodo-2,3-dihydropyridazin-3-one Property
- Melting point:
- 147-148 ºC
- Density
- 2.40
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- pka
- 10.27±0.40(Predicted)
- Appearance
- Light yellow to green yellow Solid
- InChI
- InChI=1S/C4H3IN2O/c5-3-1-4(8)7-6-2-3/h1-2H,(H,7,8)
- InChIKey
- UZWMMCWOUBWROK-UHFFFAOYSA-N
- SMILES
- C1(=O)NN=CC(I)=C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- SYX00367
- Product name
- 5-Iodo-3(2H)-pyridazinone
- Packaging
- 1g
- Price
- $216
- Updated
- 2025/07/31
- Product number
- I737690
- Product name
- 5-Iodo-2,3-dihydropyridazin-3-one
- Packaging
- 500mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- 115336
- Product name
- 5-Iodo-3(2H)-pyridazinone
- Purity
- 95%
- Packaging
- 1g
- Price
- $78
- Updated
- 2021/12/16
- Product number
- W8629
- Product name
- 5-Iodo-2,3-dihydropyridazin-3-one
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 115336
- Product name
- 5-Iodo-3(2H)-pyridazinone
- Purity
- 95%
- Packaging
- 5g
- Price
- $351
- Updated
- 2021/12/16
5-Iodo-2,3-dihydropyridazin-3-one Chemical Properties,Usage,Production
Synthesis
932-22-9
825633-94-1
General procedure for the synthesis of 5-iodopyridazin-3(2H)-one from 4,5-dichloropyridazin-3(2H)-one: In a sealed tube, 4,5-dichloropyridazin-3(2H)-one (10 g, 60.61 mmol) was mixed with 47% hydriodic acid (75 mL), and the reaction mixture was heated at 150 °C for 25 hours. Upon completion of the reaction, the mixture was filtered and the solid was washed with deionized water (100 mL). Subsequently, the solids were suspended in deionized water (200 mL), heated to 50 °C and sodium thiosulfate was slowly added with stirring until the solution took on a light brown color and precipitate formation was observed. The resulting mixture was filtered and the filtrate was dried under vacuum. The brown solid obtained was washed with ethanol (200 mL) preheated to about 78 °C and filtered again. The red to brown filtrate was dried under vacuum. Finally, the dark brown solid obtained was ground with dichloromethane (20 mL) followed by hexane (4 x 30 mL) and dried under vacuum to give 5-iodo-2H-pyridazin-3-one (8.640 g, 64% yield) as a brown solid. The product could be used in the subsequent reaction without further purification.
References
[1] Patent: US2009/264434, 2009, A1. Location in patent: Page/Page column 29; 47
[2] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 12, p. 3880 - 3886
[3] Patent: WO2009/142732, 2009, A2. Location in patent: Page/Page column 65-66
[4] Patent: WO2009/152325, 2009, A1. Location in patent: Page/Page column 208-209
[5] Patent: US2008/27041, 2008, A1. Location in patent: Page/Page column 78
5-Iodo-2,3-dihydropyridazin-3-one Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Iodo-2,3-dihydropyridazin-3-one manufacturers
- Product
- 5-Iodo-2,3-dihydropyridazin-3-one 825633-94-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-11-02
- Product
- 5-Iodo-2,3-dihydropyridazin-3-one 825633-94-1
- Price
- US $1.00/EA
- Min. Order
- 100g
- Purity
- 98%min
- Supply Ability
- G/KG/T
- Release date
- 2019-12-20