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N-Boc-2-(4-aminophenyl)ethanol

Product Name
N-Boc-2-(4-aminophenyl)ethanol
CAS No.
104060-23-3
Chemical Name
N-Boc-2-(4-aminophenyl)ethanol
Synonyms
N-Boc-2-(4-Aminophenyl);2-[4-(Boc-amino)phenyl]ethanol;N-Boc-2-(4-aminophenyl)ethanol;tert-Butyl (4-(2-hydroxyethyl)phenyl)carbamate;tert-butyl N-[4-(2-hydroxyethyl)phenyl]carbamate;Carbamic acid, N-[4-(2-hydroxyethyl)phenyl]-, 1,1-dimethylethyl ester
CBNumber
CB22471109
Molecular Formula
C13H19NO3
Formula Weight
237.29
MOL File
104060-23-3.mol
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N-Boc-2-(4-aminophenyl)ethanol Property

storage temp. 
Sealed in dry,Room Temperature
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B619675
Product name
N-Boc-2-(4-Aminophenyl)ethanol
Packaging
100mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
072009
Product name
N-Boc-2-(4-aminophenyl)ethanol
Purity
95+%
Packaging
1g
Price
$32
Updated
2021/12/16
AK Scientific
Product number
X8689
Product name
N-Boc-2-(4-aminophenyl)ethanol
Packaging
1g
Price
$77
Updated
2021/12/16
Matrix Scientific
Product number
072009
Product name
N-Boc-2-(4-aminophenyl)ethanol
Purity
95+%
Packaging
5g
Price
$88
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140389
Product name
tert-Butyl (4-(2-hydroxyethyl)phenyl)carbamate
Packaging
5G
Price
$93
Updated
2021/12/16
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N-Boc-2-(4-aminophenyl)ethanol Chemical Properties,Usage,Production

Synthesis

24424-99-5

104-10-9

104060-23-3

Step 1. Preparation of tert-butyl 4-(2-hydroxyethyl)phenylcarbamate: Di-tert-butyl dicarbonate (1.75 g, 8.01 mmol) was added to a solution of ethyl acetate (10 ml) of 2-(4-aminophenyl)ethanol (1 g, 7.28 mmol). The reaction mixture was stirred at room temperature for 24 hours. After completion of the reaction, the reaction mixture was extracted by adding water and ethyl acetate to the reaction mixture. The organic layer was dried with anhydrous magnesium sulfate and the solvent was subsequently removed under reduced pressure. The residue was purified by column chromatography (n-hexane:ethyl acetate=1:2) to afford 1.72 g (Yield: 99%, white solid) of N-Boc-2-(4-aminophenyl)ethanol.1H NMR (400 MHz, CDCl3): δ7.29 (d, J=8.4 Hz, 2H), 7.16 (d, J=8.4 Hz, 2H), 6.45 ( br s, 1H), 3.82(br s, 2H), 2.81(t, J=6.6Hz, 2H), 1.52(s, 9H).

References

[1] Medicinal Chemistry Research, 2003, vol. 11, # 7, p. 380 - 398
[2] Patent: WO2009/61131, 2009, A2. Location in patent: Page/Page column 50
[3] Patent: WO2004/65402, 2004, A1. Location in patent: Page/Page column 148-149
[4] Patent: US6362360, 2002, B1. Location in patent: Example 1
[5] Patent: US2003/18207, 2003, A1

N-Boc-2-(4-aminophenyl)ethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-2-(4-aminophenyl)ethanol Suppliers

China 39 Germany 1 India 1 United Kingdom 1 United States 6 Global 48
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58

104060-23-3, N-Boc-2-(4-aminophenyl)ethanolRelated Search:


  • N-Boc-2-(4-aminophenyl)ethanol
  • tert-Butyl (4-(2-hydroxyethyl)phenyl)carbamate
  • N-Boc-2-(4-Aminophenyl)
  • tert-butyl N-[4-(2-hydroxyethyl)phenyl]carbamate
  • Carbamic acid, N-[4-(2-hydroxyethyl)phenyl]-, 1,1-dimethylethyl ester
  • 2-[4-(Boc-amino)phenyl]ethanol
  • 104060-23-3