Fmoc-D-homoArg(Et)2-OH·HCl

Product Name: Fmoc-D-homoArg(Et)2-OH·HCl
CAS No.: 2098497-24-4
Chemical Name: Fmoc-D-homoArg(Et)2-OH·HCl
Synonyms: Fmoc-D-homoArg(Et;Fmoc-D-homoArg(Et)2-OH·HCl;Fmoc-D-HomoArg(Et)2-0H.HC1;Fmoc-D-homoArg(Et)2-OH (hydrochloride);Fmoc-d-homoarg(et)2-oh hydrochloride salt;Fmoc-D-Har(Et)2-OH/Fmoc-D-HomoArg(Et)2-OH.HCl(symmetrical);(2R)-6-[[amino(diethylamino)methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid;(2R)-6-[(E)-N',N''-diethylcarbamimidamido]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid hydrochloride
CBNumber: CB22475066
Molecular Formula: C26H35ClN4O4
Formula Weight: 503.04
MOL File: 2098497-24-4.mol

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Hazard and Precautionary Statements (GHS)

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Fmoc-D-homoArg(Et)2-OH·HCl Chemical Properties,Usage,Production

Uses

Fmoc-D-homoArg(Et)2-OH (hydrochloride) is a Fmoc-protected derivative of D-Homoarginine (HArg) that renders peptides and proteins resistant to proteolysis by trypsin. Fmoc-D-homoArg(Et)2-OH (hydrochloride) can be used as a cleavable ADC linker to synthesize antibody-drug conjugates (ADCs)[1].

References

[1] Zhu R, et al. An Efficient and Economical Method for the Preparation of Fmoc‐Argω, ω′(Boc) 2‐OH[J]. Chinese Journal of Chemistry, 2010, 28(8): 1508-1509.

Fmoc-D-homoArg(Et)2-OH·HCl Preparation Products And Raw materials

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Fmoc-D-homoArg(Et)2-OH·HCl Suppliers

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2098497-24-4, Fmoc-D-homoArg(Et)2-OH·HClRelated Search:

FMoc-D-4-Aph(tBu-CbM)-OH Fmoc-3-(2-Naphthyl)-D-alanine Fmoc-N-Me-Tyr(tBu)-OH FMOC-D-CIT-OH FMOC-D-alanine (9H-Fluoren-9-yl)MethOxy]Carbonyl HomoArg(Et)2-OH·HCl (symmetrical) FMOC-D-4-Chlorophe FMOC-LYS(BOC)(ISOPROPYL)-OH Fmoc-Lys(nicotinoyl)-OH (R)-N-Acetyl-2-naphthylalanine Fmoc-D-Asn(Trt)-OH 4-[(AMinocarbonyl)aMino]-N-[(9H-fluoren-9-ylMethoxy)carbonyl]-D-phenylalanine Fmoc-Lys(Pal-Glu-OtBu)-OH (R)-N-Fmoc-(3-Pyridyl)alanine N-[(9H-Fluoren-9-ylMethoxy)carbonyl]-4-[[[(4S)-hexahydro-2,6-dioxo-4-pyriMidinyl]carbonyl]aMino]-L-phenylalanine

Fmoc-D-homoArg(Et)2-OH·HCl

Fmoc-D-Har(Et)2-OH/Fmoc-D-HomoArg(Et)2-OH.HCl(symmetrical)

(2R)-6-[(E)-N',N''-diethylcarbamimidamido]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid hydrochloride

(2R)-6-[[amino(diethylamino)methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid

Fmoc-d-homoarg(et)2-oh hydrochloride salt

Fmoc-D-homoArg(Et

Fmoc-D-homoArg(Et)2-OH (hydrochloride)

Fmoc-D-HomoArg(Et)2-0H.HC1

2098497-24-4

C26H34N4O4ClH