Prosaptide TX14(A)
- Product Name
- Prosaptide TX14(A)
- CAS No.
- 196391-82-9
- Chemical Name
- Prosaptide TX14(A)
- Synonyms
- Prosaptide TX14(A);Prosaptide TX14(A) TFA salt;THR-D-ALA-LEU-ILE-ASP-ASN-ASN-ALA-THR-GLU-GLU-ILE-LEU-TYR;L-Tyrosine, L-threonyl-D-alanyl-L-leucyl-L-isoleucyl-L-α-aspartyl-L-asparaginyl-L-asparaginyl-L-alanyl-L-threonyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-leucyl-
- CBNumber
- CB22477136
- Molecular Formula
- C69H110N16O26
- Formula Weight
- 1579.73
- MOL File
- 196391-82-9.mol
Prosaptide TX14(A) Property
- Boiling point:
- 1954.9±65.0 °C(Predicted)
- Density
- 1.326±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- form
- Powder
- pka
- 3.08±0.10(Predicted)
- color
- White to off-white
- Water Solubility
- Soluble to 2 mg/ml in water
- Sequence
- Thr-Ala-Leu-Ile-Asp-Asn-Asn-Ala-Thr-Glu-Glu-Ile-Leu-Tyr
N-Bromosuccinimide Price
- Product number
- SML1417
- Product name
- Prosaptide Tx 14(A) trifluoroacetate salt
- Purity
- ≥95% (HPLC)
- Packaging
- 1 mg
- Price
- $207
- Updated
- 2025/07/31
- Product number
- 5151
- Product name
- ProsaptideTX14(A)
- Packaging
- 1
- Price
- $182
- Updated
- 2021/12/16
- Product number
- P839070
- Product name
- ProsaptideTx14(A)
- Packaging
- 10mg
- Price
- $1100
- Updated
- 2021/12/16
- Product number
- P839070
- Product name
- ProsaptideTx14(A)
- Packaging
- 1mg
- Price
- $220
- Updated
- 2021/12/16
- Product number
- B7763
- Product name
- ProsaptideTX14(A)
- Packaging
- 1mg
- Price
- $266
- Updated
- 2021/12/16
Prosaptide TX14(A) Chemical Properties,Usage,Production
Uses
Prosaptide Tx 14(A) is a prosaposin-derived peptide with neuroprotective properties. It is able to cross the blood-brain barrier and a potential therapeutic agent for treating neurodegenerative diseases.
Biological Activity
Prosaptide Tx 14(A) is a potent agonist of G protein-coupled receptors GPR37 (also known as Parkin-associated endothelin receptor-like receptor Pael-R) and GPR37L1. Prosaptide Tx 14(A) is the active fragment of prosaposin, a secreted neuroprotective and glioprotective factor. Prosaptide Tx 14(A) has EC50 values of 5 nM for GPR37L1 and 7 nM for GPR37, and has also been shown to have some GSK3 inhibitory properties. Prosaptide has been shown to improve nerve regeneration in diabetic rats, to reduce neuropathic pain, and to protect dopaminergic neurons in animal models of Parkinson disease.
storage
Store at -20°C
Prosaptide TX14(A) Preparation Products And Raw materials
Raw materials
Preparation Products
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