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DMEOB

Product Name
DMEOB
CAS No.
40252-74-2
Chemical Name
DMEOB
Synonyms
DMEOB;bis(3-methoxybenzylidene)hydrazine;1,2-Bis(3-methoxybenzylidene)hydrazine;3-METHOXYBENZALDEHYDE [(3-METHOXYPHENYL)METHYLENE]HYDRAZONE;[(3-METHOXYPHENYL)METHYLENE]HYDRAZONE-3-METHOXYBENZALDEHYDE;Benzaldehyde, 3-methoxy-, 2-[(3-methoxyphenyl)methylene]hydrazone
CBNumber
CB2247801
Molecular Formula
C16H16N2O2
Formula Weight
268.31
MOL File
40252-74-2.mol
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DMEOB Property

Melting point:
77-78 °C(Solv: ethanol (64-17-5))
Boiling point:
405.1±45.0 °C(Predicted)
Density 
1.05±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: insoluble
form 
solid
pka
6.46±0.50(Predicted)
color 
yellow
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Safety

Hazard Codes 
Xi,N
Risk Statements 
41-50/53
Safety Statements 
26-36/37/39-60-61
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D6317
Product name
DMeOB
Purity
≥98% (HPLC), solid
Packaging
50mg
Price
$408
Updated
2024/03/01
TRC
Product number
D494403
Product name
DMEOB
Packaging
10mg
Price
$55
Updated
2021/12/16
Usbiological
Product number
255167
Product name
DMeOB
Packaging
10mg
Price
$353
Updated
2021/12/16
ApexBio Technology
Product number
B6897
Product name
DMeOB
Packaging
10mg
Price
$119
Updated
2021/12/16
ApexBio Technology
Product number
B6897
Product name
DMeOB
Packaging
50mg
Price
$497
Updated
2021/12/16
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DMEOB Chemical Properties,Usage,Production

Uses

DMEOB is a negative allosteric modulator at mGluR-5 (1). These mGlu receptors maintain a modulatory role and act as drug targets for various neurological disorders including depression, schizophrenia and Parkinson’s.

Biological Activity

Negative allosteric modulator of the metabotropic glutamate receptor mGlu 5 ; displays reversible non-competitive inhibition of mGlu 5 -mediated responses (IC 50 = 3 μ M).

Biochem/physiol Actions

Negative allosteric modulator at the metabotropic glutamate receptor mGluR5.

DMEOB Preparation Products And Raw materials

Raw materials

Preparation Products

40252-74-2, DMEOBRelated Search:


  • DMEOB
  • [(3-METHOXYPHENYL)METHYLENE]HYDRAZONE-3-METHOXYBENZALDEHYDE
  • 3-METHOXYBENZALDEHYDE [(3-METHOXYPHENYL)METHYLENE]HYDRAZONE
  • bis(3-methoxybenzylidene)hydrazine
  • Benzaldehyde, 3-methoxy-, 2-[(3-methoxyphenyl)methylene]hydrazone
  • 1,2-Bis(3-methoxybenzylidene)hydrazine
  • 40252-74-2
  • Glutamate receptor