Pardoprunox

Product Name: Pardoprunox
CAS No.: 269718-84-5
Chemical Name: Pardoprunox
Synonyms: SLV-308;DU 126891;Pardoprunox;SLV-308; DU-126891;pardoprunox (SLV308);Pardoprunox，DU 126891;7-(4-Methyl-1-piperazinyl)-2(3H)-benzoxazolone;2(3H)-Benzoxazolone, 7-(4-methyl-1-piperazinyl)-;7-(4-methylpiperazin-1-yl)-3H-1,3-benzoxazol-2-one
CBNumber: CB22498836
Molecular Formula: C12H15N3O2
Formula Weight: 233.27
MOL File: 269718-84-5.mol

More

Less

Pardoprunox Property

Density: 1.258±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 9.15±0.70(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0009657
Product name: PARDOPRUNOX
Purity: 95.00%
Packaging: 5MG
Price: $501.07
Updated: 2021/12/16

Crysdot

Product number: CD31002453
Product name: Pardoprunox
Purity: 98+%
Packaging: 5mg
Price: $525
Updated: 2021/12/16

DC Chemicals

Product number: DC6911
Product name: pardoprunox(SLV308)
Purity: >98%
Packaging: 250mg
Price: $1100
Updated: 2021/12/16

Chemenu

Product number: CM161552
Product name: 7-(4-methylpiperazin-1-yl)benzo[d]oxazol-2(3H)-one
Purity: 98%
Packaging: 100mg
Price: $1374
Updated: 2021/12/16

AccelPharmtech

Product number: E2902
Product name: 7-(4-methyl-1-piperazinyl)-2(3H)-Benzoxazolone
Purity: 97.00%
Packaging: 1G
Price: $1760
Updated: 2021/12/16

More

Less

Pardoprunox Chemical Properties,Usage,Production

Uses

Pardoprunox (SLV-308) is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively[1].

IC 50

5-HT_1A Receptor: 6.3 (pEC₅₀); D₂ Receptor: 8 (pEC₅₀); D₃ Receptor: 9.2 (pEC₅₀)

References

[1] Glennon JC, et al. In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist. Synapse. 2006 Dec 15;60(8):599-608. DOI:10.1002/syn.20330
[2] Bronzova J, et al. Double-blind study of pardoprunox, a new partial dopamine agonist, in early Parkinson's disease. Mov Disord. 2010 Apr 30;25(6):738-46. DOI:10.1002/mds.22948
[3] Bétry C, et al. In vivo effects of pardoprunox (SLV308), a partial D?/D? receptor and 5-HT1A receptor agonist, on rat dopamine and serotonin neuronal activity. Synapse. 2011 Oct;65(10):1042-51. DOI:10.1002/syn.20936

Pardoprunox Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Pardoprunox Suppliers

China 42 United States 8 Global 50

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 12476
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

Shanghai Biopharmaleader Co., Ltd.

Tel: +86 18721201413
Fax: +86 (21) 5775-8967
Email: sales@biopharmaleader.com
Country: China
ProdList: 1720
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3276
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

269718-84-5, PardoprunoxRelated Search:

Palonosetron Peramivir trihydrate

Pardoprunox

DU 126891

pardoprunox (SLV308)

SLV-308

SLV-308; DU-126891

Pardoprunox，DU 126891

7-(4-Methyl-1-piperazinyl)-2(3H)-benzoxazolone

7-(4-methylpiperazin-1-yl)-3H-1,3-benzoxazol-2-one

2(3H)-Benzoxazolone, 7-(4-methyl-1-piperazinyl)-

269718-84-5

Inhibitors