ChemicalBook > CAS DataBase List > 1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride

1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride

Product Name
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride
CAS No.
850352-11-3
Chemical Name
1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride
Synonyms
Energy-1;Naphyrone HCl;b-Naphyrone Hydrochloride;Naphyrone (hydrochloride);Naphyrone hydrochloride solution;2-Naphthyl Pyrovalerone Hydrochloride;O-2482 Naphthylpyrovalerone or Naphyrone;1-(2-naphthyl)-2-(1-pyrrolidinyl)-1-pentanone;Naphyrone (hydrochloride) (exempt preparation);Naphyrone.HCl, 1mg/ml in Methanol (as free base)
CBNumber
CB22499222
Molecular Formula
C19H24ClNO
Formula Weight
317.85296
MOL File
850352-11-3.mol
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1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride Property

Melting point:
>189°C (dec.)
Flash point:
9℃
storage temp. 
Refrigerator
solubility 
Methanol (Slightly)
form 
Solid
color 
Pale Yellow to Pale Beige
Major Application
forensics and toxicology
InChI
1S/C19H23NO.ClH/c1-2-7-18(20-12-5-6-13-20)19(21)17-11-10-15-8-3-4-9-16(15)14-17;/h3-4,8-11,14,18H,2,5-7,12-13H2,1H3;1H
InChIKey
SIOVYKZRZLWQSY-UHFFFAOYSA-N
SMILES
CCCC(N1CCCC1)C(C2=CC(C=CC=C3)=C3C=C2)=O.[H]Cl
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Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
Storage Class
3 - Flammable liquids
Hazard Classifications
Acute Tox. 3 Dermal
Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
Flam. Liq. 2
STOT SE 1
DEA Controlled Substances
CSCN: 1258
CSA SCH: Schedule I
NARC: No
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N-067
Product name
Naphyrone hydrochloride
Purity
1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$306
Updated
2026/04/30
Cayman Chemical
Product number
10517
Product name
Naphyrone (hydrochloride)
Purity
≥97%
Packaging
1mg
Price
$69
Updated
2026/04/30
Cayman Chemical
Product number
10517
Product name
Naphyrone (hydrochloride)
Purity
≥97%
Packaging
5mg
Price
$183
Updated
2026/04/30
Cayman Chemical
Product number
16056
Product name
Naphyrone (hydrochloride) (exempt preparation)
Purity
≥97%
Packaging
1mg
Price
$69
Updated
2026/04/30
Cayman Chemical
Product number
10517
Product name
Naphyrone (hydrochloride)
Purity
≥97%
Packaging
10mg
Price
$329
Updated
2026/04/30
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1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride Chemical Properties,Usage,Production

Description

Pyrovalerone is a psychoactive compound with stimulatory effects. It is a controlled drug that has been found as a contaminant in products sold as bath salts. Naphyrone (hydrochloride) is an analog of pyrovalerone that is characterized by the substitution of the methylphenyl group of pyrovalerone with a naphthyl group. Naphyrone potently inhibits dopamine, serotonin, and norepinephrine transporters (IC50 = 20, 33, and 136 nM, respectively). Naphyrone, like pyrovalerone, has been detected in bath salt-type products. This compound is intended for forensic and research purposes.

Chemical Properties

Pale Yellow Solid

Uses

A Pyrovalerone (P997750) analog as selective dopamine transporter inhibitors.

References

[1] PETER C. MELTZER. 1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) Analogues: A Promising Class of Monoamine Uptake Inhibitors[J]. Journal of Medicinal Chemistry, 2006, 49 4: 1420-1432. DOI: 10.1021/jm050797a
[2] LAURIANE TREMEAU-CAYEL . A comparison of single quadrupole mass detection and diode array ultraviolet detection interfaced to ultra-high performance supercritical chromatography for the quantitative analysis of synthetic cathinones[J]. Journal of Chromatography B, 2018, 1091: Pages 96-100. DOI: 10.1016/j.jchromb.2018.05.035

1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride Suppliers

Canada 1 China 12 India 1 United States 2 Global 16
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
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60
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939; 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
15781
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55
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
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50
AN PharmaTech Co Ltd
Tel
86(21)68097365
Fax
86(21)33321566
Email
sales@anpharma.net
Country
China
ProdList
4891
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55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
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Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
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sales@glpbio.cn
Country
China
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
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sales@chemegen.com
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China
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11218
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Chengdu Peter-like Biotechnology Co., Ltd.
Tel
028-81700200 13308200041
Email
2851167782@qq.com
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China
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10940
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58
Cayman Chemical Company
Tel
800-364-9897
Email
sales@caymanchem.com
Country
China
ProdList
6838
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58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
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6038
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850352-11-3, 1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochlorideRelated Search:


  • 1-(Naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one hydrochloride
  • 1-(2-naphthyl)-2-(1-pyrrolidinyl)-1-pentanone
  • 1-(2-Naphthalenyl)-2-(1-pyrrolidinyl)-1-pentanone Hydrochloride
  • 1-(naphthalen-2-yl)-2-(pyrrolidin-1-yl)pentan-1-one HCl
  • 2-Naphthyl Pyrovalerone Hydrochloride
  • Naphyrone (hydrochloride)
  • b-Naphyrone Hydrochloride
  • O-2482 Naphthylpyrovalerone or Naphyrone
  • Energy-1
  • Naphyrone hydrochloride solution
  • Naphyrone (hydrochloride) (exempt preparation)
  • Naphyrone HCl
  • 1-Pentanone, 1-(2-naphthalenyl)-2-(1-pyrrolidinyl)-, hydrochloride (1:1)
  • 1-(2-naphthalenyl)-2-(1-pyrrolidinyl)-1-Pentanone hydrochloride (1:1)
  • Naphyrone.HCl, 1mg/ml in Methanol (as free base)
  • Naphyrone Hydrochloride (1-Naphthalen-2-yl-2-pyrrolidin-1-ylpentan-1-one Hydrochloride) 1.0 mg/ml in Methanol (as free base)
  • Naphyrone Hydrochloride (1-Naphthalen-2-yl-2-pyrrolidin-1-ylpentan-1-one Hydrochloride)
  • 850352-11-3
  • Aromatics
  • Drug Analogues
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals