ChemicalBook > CAS DataBase List > 5-Chloro-4-(trifluoromethyl)pyridin-2-amine

5-Chloro-4-(trifluoromethyl)pyridin-2-amine

Product Name
5-Chloro-4-(trifluoromethyl)pyridin-2-amine
CAS No.
1095823-39-4
Chemical Name
5-Chloro-4-(trifluoromethyl)pyridin-2-amine
Synonyms
5-Chloro-4-(trifluoromethyl);5-Chloro-4-(trifluoromethyl)pyridin-2-amine;5-Chloro-4-(trifluoromethyl)-2-pyridinamine;5-chloro-4-(trifluoromethyl)pyridin-3-amine;5-Chloro-4-trifluoromethyl-pyridin-2-ylamine;2-PyridinaMine, 5-chloro-4-(trifluoroMethyl)-;2- amino -4- three fluoromethyl -5- chlorpyridine
CBNumber
CB22504805
Molecular Formula
C6H4ClF3N2
Formula Weight
196.56
MOL File
1095823-39-4.mol
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5-Chloro-4-(trifluoromethyl)pyridin-2-amine Property

Boiling point:
258.3±40.0 °C(Predicted)
Density 
1.507±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
powder
pka
2.47±0.24(Predicted)
color 
Yellow
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
C597268
Product name
5-Chloro-4-(trifluoromethyl)pyridin-2-amine
Packaging
500mg
Price
$310
Updated
2021/12/16
Matrix Scientific
Product number
119401
Product name
5-Chloro-4-(trifluoromethyl)pyridin-2-amine
Purity
95+%
Packaging
1g
Price
$345
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0367270
Product name
5-CHLORO-4-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE
Purity
95.00%
Packaging
250MG
Price
$292.95
Updated
2021/12/16
Matrix Scientific
Product number
119401
Product name
5-Chloro-4-(trifluoromethyl)pyridin-2-amine
Purity
95+%
Packaging
5g
Price
$1195
Updated
2021/12/16
Apolloscientific
Product number
PC01524
Product name
2-Amino-5-chloro-4-(trifluoromethyl)pyridine
Packaging
250mg
Price
$26
Updated
2021/12/16
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5-Chloro-4-(trifluoromethyl)pyridin-2-amine Chemical Properties,Usage,Production

Synthesis

106447-97-6

1095823-39-4

Synthesis of Compound A.6: To a solution of 2-amino-4-trifluoromethylpyridine (2.00 g, 12.3 mmol) in N,N-dimethylformamide (DMF, 4 mL) was slowly added a solution of 1,3-dichloro-5,5-dimethylglycolide (1.4 g, 7.4 mmol) in DMF (4 mL). The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the mixture was diluted with ether (80 mL) and washed with deionized water (10 mL). The organic phase was separated, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by fast column chromatography (eluent: 0-20% ethyl acetate/hexane) to afford compound A.6 as a light yellow oil in 65% yield.1H NMR (DMSO-d6) δ: 8.16 (s, 1H), 6.87 (s, 1H), 6.76 (br s, 1H); MS: m/z 197 [M + H]+.

References

[1] Patent: US2009/5359, 2009, A1. Location in patent: Page/Page column 33
[2] Patent: US2009/36419, 2009, A1. Location in patent: Page/Page column 78
[3] Patent: WO2010/78408, 2010, A1. Location in patent: Page/Page column 86; 87; 88

5-Chloro-4-(trifluoromethyl)pyridin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-Chloro-4-(trifluoromethyl)pyridin-2-amine manufacturers

Honest Joy Holdings Limited
Product
5-Chloro-4-(trifluoromethyl)pyridin-2-amine 1095823-39-4
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
100 tons
Release date
2022-01-14
Career Henan Chemical Co
Product
5-Chloro-4-(trifluoromethyl)pyridin-2-amine 1095823-39-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KGS
Release date
2019-12-25

1095823-39-4, 5-Chloro-4-(trifluoromethyl)pyridin-2-amineRelated Search:


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  • 5-chloro-4-(trifluoromethyl)pyridin-3-amine
  • 5-Chloro-4-(trifluoromethyl)
  • 2- amino -4- three fluoromethyl -5- chlorpyridine
  • 5-Chloro-4-(trifluoromethyl)-2-pyridinamine
  • 1095823-39-4