5-Chloro-4-(trifluoromethyl)pyridin-2-amine
- Product Name
- 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
- CAS No.
- 1095823-39-4
- Chemical Name
- 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
- Synonyms
- 5-Chloro-4-(trifluoromethyl);5-Chloro-4-(trifluoromethyl)pyridin-2-amine;5-Chloro-4-(trifluoromethyl)-2-pyridinamine;5-chloro-4-(trifluoromethyl)pyridin-3-amine;5-Chloro-4-trifluoromethyl-pyridin-2-ylamine;2-PyridinaMine, 5-chloro-4-(trifluoroMethyl)-;2- amino -4- three fluoromethyl -5- chlorpyridine
- CBNumber
- CB22504805
- Molecular Formula
- C6H4ClF3N2
- Formula Weight
- 196.56
- MOL File
- 1095823-39-4.mol
5-Chloro-4-(trifluoromethyl)pyridin-2-amine Property
- Boiling point:
- 258.3±40.0 °C(Predicted)
- Density
- 1.507±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- powder
- pka
- 2.47±0.24(Predicted)
- color
- Yellow
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- C597268
- Product name
- 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
- Packaging
- 500mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- 119401
- Product name
- 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $345
- Updated
- 2021/12/16
- Product number
- HCH0367270
- Product name
- 5-CHLORO-4-(TRIFLUOROMETHYL)PYRIDIN-2-AMINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $292.95
- Updated
- 2021/12/16
- Product number
- 119401
- Product name
- 5-Chloro-4-(trifluoromethyl)pyridin-2-amine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $1195
- Updated
- 2021/12/16
- Product number
- PC01524
- Product name
- 2-Amino-5-chloro-4-(trifluoromethyl)pyridine
- Packaging
- 250mg
- Price
- $26
- Updated
- 2021/12/16
5-Chloro-4-(trifluoromethyl)pyridin-2-amine Chemical Properties,Usage,Production
Synthesis
106447-97-6
1095823-39-4
Synthesis of Compound A.6: To a solution of 2-amino-4-trifluoromethylpyridine (2.00 g, 12.3 mmol) in N,N-dimethylformamide (DMF, 4 mL) was slowly added a solution of 1,3-dichloro-5,5-dimethylglycolide (1.4 g, 7.4 mmol) in DMF (4 mL). The reaction mixture was stirred at room temperature for 2 hours. After completion of the reaction, the mixture was diluted with ether (80 mL) and washed with deionized water (10 mL). The organic phase was separated, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product. The crude product was purified by fast column chromatography (eluent: 0-20% ethyl acetate/hexane) to afford compound A.6 as a light yellow oil in 65% yield.1H NMR (DMSO-d6) δ: 8.16 (s, 1H), 6.87 (s, 1H), 6.76 (br s, 1H); MS: m/z 197 [M + H]+.
References
[1] Patent: US2009/5359, 2009, A1. Location in patent: Page/Page column 33
[2] Patent: US2009/36419, 2009, A1. Location in patent: Page/Page column 78
[3] Patent: WO2010/78408, 2010, A1. Location in patent: Page/Page column 86; 87; 88
5-Chloro-4-(trifluoromethyl)pyridin-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Chloro-4-(trifluoromethyl)pyridin-2-amine manufacturers
- Product
- 5-Chloro-4-(trifluoromethyl)pyridin-2-amine 1095823-39-4
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14
- Product
- 5-Chloro-4-(trifluoromethyl)pyridin-2-amine 1095823-39-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-25