ChemicalBook > CAS DataBase List > Necrosis Inhibitor, IM-54

Necrosis Inhibitor, IM-54

Product Name: Necrosis Inhibitor, IM-54
CAS No.: 861891-50-1
Chemical Name: Necrosis Inhibitor, IM-54
Synonyms: IM-54;IM-54 ，E2178;Necrosis Inhibitor, IM-54;2-(1H-Indol-3-yl)-3-pentylamino-maleimide;IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide);Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem;1-methyl-3-(1-methylindol-3-yl)-4-(pentylamino)pyrrole-2,5-dione;IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide), Necrosis inhibitor;1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-
CBNumber: CB22514666
Molecular Formula: C19H23N3O2
Formula Weight: 325.4
MOL File: 861891-50-1.mol

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Necrosis Inhibitor, IM-54 Property

Boiling point:: 511.5±50.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: soluble5mg/mL (clear solution)
form: Yellow orange solid
pka: 1.96±0.20(Predicted)
color: light orange to dark orange

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HazardClass: 6.1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P321Specific treatment (see … on this label).

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0412
Product name: IM-54
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $203
Updated: 2025/07/31

Sigma-Aldrich

Product number: 480060
Product name: Necrosis Inhibitor, IM-54
Packaging: 5mg
Price: $226
Updated: 2025/07/31

Cayman Chemical

Product number: 13323
Product name: IM-54
Purity: ≥95%
Packaging: 1mg
Price: $31
Updated: 2024/03/01

Cayman Chemical

Product number: 13323
Product name: IM-54
Purity: ≥95%
Packaging: 5mg
Price: $133
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0412
Product name: IM-54
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $696
Updated: 2022/05/15

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Necrosis Inhibitor, IM-54 Chemical Properties,Usage,Production

Uses

Necrosis Inhibitor, IM-54 is a selective inhibitor of oxidative stress-induced necrotic cell death.

Definition

ChEBI: IM-54 is an organonitrogen compound and an organooxygen compound. It is functionally related to an alpha-amino acid.

Biological Activity

IM-54 is a cell permeable, potent and selective inhibitor of necrosis. The compound inhibits necrosis induced by oxidative stress. IM-54 does not inhibit apoptosis induced by anticancer drugs.

Necrosis Inhibitor, IM-54 Preparation Products And Raw materials

Raw materials

Preparation Products

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861891-50-1, Necrosis Inhibitor, IM-54Related Search:

Necrosis Inhibitor, IM-54

IM-54

1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione

2-(1H-Indol-3-yl)-3-pentylamino-maleimide

1-methyl-3-(1-methylindol-3-yl)-4-(pentylamino)pyrrole-2,5-dione

IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide)

Necrosis Inhibitor, IM-54 - CAS 861891-50-1 - Calbiochem

1H-Pyrrole-2,5-dione, 1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-

1-Methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione , IM-54

IM 54 (2-(1H-Indol-3-yl)-3-pentylamino-maleimide), Necrosis inhibitor

IM-54 ，E2178

861891-50-1

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