3-bromo-4-trifluoromethoxyanisole
- Product Name
- 3-bromo-4-trifluoromethoxyanisole
- CAS No.
- 1049730-91-7
- Chemical Name
- 3-bromo-4-trifluoromethoxyanisole
- Synonyms
- 3-bromo-4-trifluoromethoxyanisole;2-BroMo-4-Methoxy-1-(trifluoroMethoxy)benzene;Benzene, 2-bromo-4-methoxy-1-(trifluoromethoxy)-
- CBNumber
- CB22514712
- Molecular Formula
- C8H6BrF3O2
- Formula Weight
- 271.03
- MOL File
- 1049730-91-7.mol
3-bromo-4-trifluoromethoxyanisole Property
- Boiling point:
- 212.8±35.0 °C(Predicted)
- Density
- 1.594±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Colorless to light yellow Liquid
N-Bromosuccinimide Price
- Product number
- B701133
- Product name
- 2-Bromo-4-methoxy-1-(trifluoromethoxy)benzene
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- HCH0363194
- Product name
- 2-BROMO-4-METHOXY-1-(TRIFLUOROMETHOXY)BENZENE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $183.75
- Updated
- 2021/12/16
- Product number
- 1112AA
- Product name
- 2-Bromo-4-methoxy-1-(trifluoromethoxy)benzene
- Packaging
- 25g
- Price
- $942
- Updated
- 2021/12/16
- Product number
- 1049730917
- Product name
- 3-Bromo-4-(trifluoromethoxy)anisole
- Packaging
- 1g
- Price
- $1519.8
- Updated
- 2021/12/16
- Product number
- A200351
- Product name
- 2-Bromo-4-methoxy-1-(trifluoromethoxy)benzene
- Purity
- 98%
- Packaging
- 250mg
- Price
- $22
- Updated
- 2021/12/16
3-bromo-4-trifluoromethoxyanisole Chemical Properties,Usage,Production
Synthesis
886496-88-4
74-88-4
1049730-91-7
Intermediate 5: Synthesis of 2-bromo-4-methoxy-1-(trifluoromethoxy)benzene; A mixture of 3-bromo-4-(trifluoromethoxy)phenol (2.0 g, 7.8 mmol), potassium carbonate (K2CO3, 1.62 g, 11.72 mmol) and iodomethane (MeI, 2.43 mL, 39.06 mmol) in acetone (13 mL) was at room temperature stirred for 10 hours. After completion of the reaction, the acetone was evaporated under reduced pressure and the crude product was diluted with dichloromethane (CH2Cl2), washed sequentially with saturated saline, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The residue was purified by column chromatography on silica gel (SiO2) using a gradient elution with hexane solution of 0 to 50% ethyl acetate (EtOAc) to afford the target product Intermediate 5 (2.10 g, 99% yield).
References
[1] Patent: WO2009/65035, 2009, A1. Location in patent: Page/Page column 67
[2] Patent: WO2008/135826, 2008, A2. Location in patent: Page/Page column 173
3-bromo-4-trifluoromethoxyanisole Preparation Products And Raw materials
Raw materials
Preparation Products
3-bromo-4-trifluoromethoxyanisole Suppliers
- Tel
- 010-59484199 18611897322
- sales@eternalchem.com
- Country
- China
- ProdList
- 4383
- Advantage
- 60
- Tel
- 13912302692 13912302692;
- Fax
- 0519-88064678
- sales@anxuanchem.com
- Country
- China
- ProdList
- 4824
- Advantage
- 58
- Tel
- 28-87999436 02887999436
- Fax
- QQ:2746983436
- sales@sano-chem.com
- Country
- China
- ProdList
- 3795
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 025-66162170
- Fax
- 025-66162170
- Country
- China
- ProdList
- 7181
- Advantage
- 55
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15491
- Advantage
- 58
- Tel
- 400-8210725 400821072
- Fax
- 021-58955996
- malulu@leyan.com
- Country
- China
- ProdList
- 24972
- Advantage
- 58
- Tel
- 021-4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52679
- Advantage
- 58
- Tel
- 021-58581007 18019463053
- Fax
- 021-50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 9732
- Advantage
- 58
- Tel
- zhiqianbio@126.com
- Country
- China
- ProdList
- 19778
- Advantage
- 58