2-(3-Methyl-4-nitrophenyl)acetic acid

Product Name: 2-(3-Methyl-4-nitrophenyl)acetic acid
CAS No.: 143665-37-6
Chemical Name: 2-(3-Methyl-4-nitrophenyl)acetic acid
Synonyms: 3-Methyl-4-nitrophenylacetic acid;3-methyl-4-nitrobenzeneacetic acid;2-(3-Methyl-4-nitrophenyl)acetic acid;Benzeneacetic acid, 3-methyl-4-nitro-;5-(Carboxymethyl)-2-nitrotoluene, 4-(Carboxymethyl)-2-methylnitrobenzene
CBNumber: CB22516291
Molecular Formula: C9H9NO4
Formula Weight: 195.17
MOL File: 143665-37-6.mol

More

Less

2-(3-Methyl-4-nitrophenyl)acetic acid Property

Boiling point:: 377.0±27.0 °C(Predicted)
Density: 1.346
storage temp.: Sealed in dry,Room Temperature
pka: 3.86±0.10(Predicted)
form: solid
color: yellow
InChI: 1S/C9H9NO4/c1-6-4-7(5-9(11)12)2-3-8(6)10(13)14/h2-4H,5H2,1H3,(H,11,12)
InChIKey: NUYOXESWWGUDLP-UHFFFAOYSA-N
SMILES: CC(C=C(CC(O)=O)C=C1)=C1[N+]([O-])=O

More

Less

Safety

WGK Germany: WGK 3
HS Code: 2916399090
Storage Class: 11 - Combustible Solids

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: MNO000158
Product name: (3-Methyl-4-nitrophenyl)acetic acid
Packaging: 1g
Price: $107
Updated: 2025/07/31

TRC

Product number: M340620
Product name: 2-(3-Methyl-4-nitrophenyl)aceticAcid
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 087181
Product name: (3-Methyl-4-nitrophenyl)acetic acid
Purity: 95%
Packaging: 1g
Price: $64
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4754-1-28
Product name: 3-Methyl-4-nitrophenylacetic acid
Packaging: 1g
Price: $136
Updated: 2021/12/16

AK Scientific

Product number: Y7532
Product name: 2-(3-Methyl-4-nitrophenyl)aceticacid
Packaging: 1g
Price: $136
Updated: 2021/12/16

More

Less

2-(3-Methyl-4-nitrophenyl)acetic acid Chemical Properties,Usage,Production

Synthesis

1350468-89-1

143665-37-6

Step 2. Synthesis of (3-methyl-4-nitrophenyl)acetic acid To a mixed solution of dimethyl (3-methyl-4-nitrophenyl) malonate (0.540 g, 2.02 mmol) in water (10 mL) and methanol (10 mL) was added potassium hydroxide (0.340 g, 6.06 mmol) at room temperature. The reaction mixture was refluxed for 4 hours. After completion of the reaction, it was cooled to room temperature and acidified with 2N aqueous hydrochloric acid solution (40 mL). The acidified solution was extracted with ethyl acetate (20 mL x 3). The organic layers were combined, dried with anhydrous magnesium sulfate, filtered, and concentrated under reduced pressure to give (3-methyl-4-nitrophenyl)acetic acid (0.480 g, quantitative yield) as an orange solid. The product was used directly in the next reaction without further purification. 1H NMR (CDCl3, 400 MHz) δ 7.97 (d, 1H), 7.28-7.26 (m, 2H), 3.71 (s, 2H), 2.61 (s, 3H).

References

[1] Patent: US2017/253569, 2017, A1. Location in patent: Paragraph 0257-0258
[2] Patent: WO2011/145022, 2011, A1. Location in patent: Page/Page column 68

2-(3-Methyl-4-nitrophenyl)acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-(3-Methyl-4-nitrophenyl)acetic acid Suppliers

China 38 India 2 Switzerland 1 United Kingdom 2 United States 10 Global 53

Record Tech (Shanghai) Co., LTD

Tel: 13761627472
Fax: 86-21-64965863
Email: 183009664@qq.com
Country: China
ProdList: 650
Advantage: 62

CEG Chemical Science&Technology Co., Ltd.

Tel: Mobile:13665161512
Fax: +86-510-68873513
Country: China
ProdList: 1785
Advantage: 58

Chimica Laboratories Co., Ltd

Tel: 0086-573-82585213
Fax: 0086-573-82585233
Email: bai@chimicalabs.com
Country: China
ProdList: 861
Advantage: 64

Nantong MYBio-pharm. Co., Ltd.

Tel: 0513-85921823 18662920231
Fax: 86-513-85012876
Email: sales@ntminyanmedical.com
Country: China
ProdList: 4206
Advantage: 58

Accela ChemBio Inc.

Tel: +1(858) 699-3322
Fax: +1(858) 876-1948
Email: marketing@accelachem.com
Country: United States
ProdList: 6024
Advantage: 65

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Chengdu Xiaojia Technology Co., Ltd.

Tel: 15902830537
Email: zhanghao@happysyn.com
Country: China
ProdList: 3175
Advantage: 55

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 10408
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

143665-37-6, 2-(3-Methyl-4-nitrophenyl)acetic acidRelated Search:

3-methyl-4-nitrobenzeneacetic acid

2-(3-Methyl-4-nitrophenyl)acetic acid

3-Methyl-4-nitrophenylacetic acid

5-(Carboxymethyl)-2-nitrotoluene, 4-(Carboxymethyl)-2-methylnitrobenzene

Benzeneacetic acid, 3-methyl-4-nitro-

143665-37-6