3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide

Product Name: 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide
CAS No.: 852918-02-6
Chemical Name: 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide
Synonyms: TCN 201;TCN 201-d5;N-[[4-(benzamidocarbamoyl)phenyl]methyl]-3-chloro-4-fluorobenzenesulfonamide;N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4-fluorobenzenesulfonaMide;4-[[[(3-Chloro-4-fluorophenyl)sulfonyl]aMino]Methyl]benzoic Acid 2-Benzoylhydrazide;3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide;Benzoic acid, 4-[[[(3-chloro-4-fluorophenyl)sulfonyl]amino]methyl]-, 2-benzoylhydrazide;TCN 201,GluN1,Inhibitor,GluN2A,inhibit,iGluR,Ionotropic glutamate receptors,NMDAR,TCN201;3-Chloro-4-fluoro-N-[(4-{[2-(phenylcarbonyl)hydrazino]carbonyl}phenyl)methyl]benzenesulfonamide;TCN-201 N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4- fluorobenzenesulfonaMide
CBNumber: CB22518750
Molecular Formula: C21H17ClFN3O4S
Formula Weight: 461.89
MOL File: 852918-02-6.mol

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3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide Property

storage temp.: 2-8°C
solubility: DMSO: soluble5mg/mL (clear solution)
form: powder
color: white to beige

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Safety

Hazard Codes: Xi
Risk Statements: 22-36/37/38
Safety Statements: 26-36/37/39
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H336May cause drowsiness or dizziness

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0416
Product name: TCN-201
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $127
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0416
Product name: TCN-201
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $511
Updated: 2024/03/01

Cayman Chemical

Product number: 19086
Product name: TCN 201
Purity: ≥95%
Packaging: 1mg
Price: $40
Updated: 2024/03/01

Cayman Chemical

Product number: 19086
Product name: TCN 201
Purity: ≥95%
Packaging: 5mg
Price: $118
Updated: 2024/03/01

Cayman Chemical

Product number: 19086
Product name: TCN 201
Purity: ≥95%
Packaging: 10mg
Price: $157
Updated: 2024/03/01

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3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide Chemical Properties,Usage,Production

Uses

Labelled TCN 201 (T012550). TCN 201 is a novel NMDA receptor antagonist selective for NR2A- over NR2B-containing receptors.

Uses

TCN 201 is a novel NMDA receptor antagonist selective for NR2A- over NR2B-containing receptors.

Biochem/physiol Actions

TCN-201 is a sulphonamide derivative, that negatively modulates glycine binding to the GluN1 (glutamate receptor subunit) subunit of the receptor.

storage

+4°C

3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide Suppliers

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Sigma-Aldrich

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852918-02-6, 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamideRelated Search:

TCN 213

3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide

TCN 201

N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4-fluorobenzenesulfonaMide

4-[[[(3-Chloro-4-fluorophenyl)sulfonyl]aMino]Methyl]benzoic Acid 2-Benzoylhydrazide

TCN 201-d5

TCN-201 N-(4-(2-benzoylhydrazinecarbonyl)benzyl)-3-chloro-4- fluorobenzenesulfonaMide

3-Chloro-4-fluoro-N-[(4-{[2-(phenylcarbonyl)hydrazino]carbonyl}phenyl)methyl]benzenesulfonamide

N-[[4-(benzamidocarbamoyl)phenyl]methyl]-3-chloro-4-fluorobenzenesulfonamide

Benzoic acid, 4-[[[(3-chloro-4-fluorophenyl)sulfonyl]amino]methyl]-, 2-benzoylhydrazide

TCN 201,GluN1,Inhibitor,GluN2A,inhibit,iGluR,Ionotropic glutamate receptors,NMDAR,TCN201

852918-02-6

C21H17ClFN3O4S

Amines

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals

Sulfur & Selenium Compounds