1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride

Product Name: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride
CAS No.: 1028969-49-4
Chemical Name: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride
Synonyms: MCOPPB;MCOPPB trihydrochloride;MCOPPB trihydrochloride hydrate;MCOPPB 3HCl,MCOPPB trihydrochloride;1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole;1H-Benzimidazole, 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-;1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole;1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride;1-(1-(1-Methylcyclooctyl)piperidin-4-yl)-2-(piperidin-3-yl)-1H-Benzo[d]imidazole trihydrochlor;1-(1-(1-Methylcyclooctyl)piperidin-4-yl)-2-(piperidin-3-yl)-1H-Benzo[d]imidazole trihydrochloride
CBNumber: CB22518770
Molecular Formula: C26H40N4
Formula Weight: 408.62
MOL File: 1028969-49-4.mol

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1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride Property

Melting point:: >249°C (dec.)
Boiling point:: 576.5±50.0 °C(Predicted)
Density: 1.18
storage temp.: Store at -20°C
solubility: H2O: ≥13mg/mL
form: powder
pka: 9.67±0.10(Predicted)
color: white to tan
Water Solubility: H2O: ≥13mg/mL

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PZ0159
Product name: MCOPPB trihydrochloride hydrate
Purity: >98% (HPLC)
Packaging: 5mg
Price: $147
Updated: 2024/03/01

Sigma-Aldrich

Product number: PZ0159
Product name: MCOPPB trihydrochloride hydrate
Purity: >98% (HPLC)
Packaging: 25mg
Price: $218.8
Updated: 2024/03/01

Tocris

Product number: 3763
Product name: MCOPPBtrihydrochloride
Purity: ≥99%(HPLC)
Packaging: 10
Price: $355
Updated: 2021/12/16

Tocris

Product number: 3763
Product name: MCOPPBtrihydrochloride
Purity: ≥99%(HPLC)
Packaging: 1
Price: $169
Updated: 2021/12/16

Usbiological

Product number: 454230
Product name: MCOPPB Trihydrochloride
Packaging: 1mg
Price: $566
Updated: 2021/12/16

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1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride Chemical Properties,Usage,Production

Uses

A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis.

Biological Activity

MCOPPB trihydrochloride is a potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. MCOPPB is the most potent novel non-peptide NOP full agonist in vitro and an orally potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting th at it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis.

1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride Suppliers

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View Lastest Price from 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride manufacturers

Career Henan Chemical Co

Product: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride 1028969-49-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-13

Career Henan Chemical Co

Product: 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride 1028969-49-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-13

1028969-49-4, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochlorideRelated Search:

1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazoletrihydrochloride

MCOPPB trihydrochloride

MCOPPB

1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole

1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole trihydrochloride hydrate

MCOPPB trihydrochloride hydrate

1-(1-(1-Methylcyclooctyl)piperidin-4-yl)-2-(piperidin-3-yl)-1H-Benzo[d]imidazole trihydrochlor

1-[1-(1-methylcyclooctyl)piperidin-4-yl]-2-[(3R)-piperidin-3-yl]benzimidazole

1-(1-(1-Methylcyclooctyl)piperidin-4-yl)-2-(piperidin-3-yl)-1H-Benzo[d]imidazole trihydrochloride

MCOPPB 3HCl,MCOPPB trihydrochloride

1H-Benzimidazole, 1-[1-(1-methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-

1028969-49-4

C26H40N4

C26H40N43HCl

C26H43Cl3N4