ChemicalBook > CAS DataBase List > 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride

1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride

Product Name
1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride
CAS No.
143692-48-2
Chemical Name
1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride
Synonyms
GYKI-53655 hydrate;GYKI 53655 hydrochloride;LY300168 hydrochloride hydrate;GYKI 53655 hydrochloride, 10 mM in DMSO;1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride;5-(4-Aminophenyl)-8,9-dihydro-N,8-dimethyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide hydrochloride
CBNumber
CB22518811
Molecular Formula
C19H21ClN4O3
Formula Weight
388.85
MOL File
143692-48-2.mol
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1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride Property

storage temp. 
Desiccate at RT
solubility 
H2O: >10mg/mL
form 
powder
color 
yellow to orange
Water Solubility 
H2O: >10mg/mL
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G7798
Product name
GYKI-53655 hydrate
Purity
>99.0% (HPLC)
Packaging
5mg
Price
$159
Updated
2024/03/01
Sigma-Aldrich
Product number
G7798
Product name
GYKI-53655 hydrate
Purity
>99.0% (HPLC)
Packaging
25mg
Price
$845
Updated
2024/03/01
Tocris
Product number
2555
Product name
GYKI53655hydrochloride
Purity
≥99%(HPLC)
Packaging
50
Price
$970
Updated
2021/12/16
Tocris
Product number
2555
Product name
GYKI53655hydrochloride
Purity
≥99%(HPLC)
Packaging
10
Price
$231
Updated
2021/12/16
Usbiological
Product number
255424
Product name
GYKI 53655 hydrochloride
Packaging
10mg
Price
$480
Updated
2021/12/16
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1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride Chemical Properties,Usage,Production

Uses

GYKI 53655 Hydrochloride is a non-competitive AMPA antagonist,.

Biological Activity

GYKI-53655 also inhibits the kainate GluK3 homomeric and GluK2/3 heteromeric receptors. It exhibits anti-ischemic, anti-convulsant, and acute neuroprotective activity.', 'GYKI-53655 is an AMPA antagonist and noncompetitive negative allosteric modulator.

storage

Room temperature (desiccate)

1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride Suppliers

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143692-48-2, 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochlorideRelated Search:


  • 1-(4-Aminophenyl)-3-methylcarbamyl-4-methyl-3,4-dihydro-7,8-methylenedioxy-5H-2,3-benzodiazepinehydrochloride
  • GYKI 53655 hydrochloride
  • 5-(4-Aminophenyl)-8,9-dihydro-N,8-dimethyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide hydrochloride
  • GYKI-53655 hydrate
  • LY300168 hydrochloride hydrate
  • GYKI 53655 hydrochloride, 10 mM in DMSO
  • 143692-48-2
  • C19H20N4O3HCl
  • C19H21N4O3Cl