3,6-dichloropicolinonitrile
- Product Name
- 3,6-dichloropicolinonitrile
- CAS No.
- 1702-18-7
- Chemical Name
- 3,6-dichloropicolinonitrile
- Synonyms
- 3,6-dichloropicolinonitrile;3,6-Dichloro-2-cyanopyridine;2-Cyano-3,6-dichloropyridine;3,6-Dichloro-2-pyridinecarbonitrile;2-Pyridinecarbonitrile, 3,6-dichloro-
- CBNumber
- CB22521239
- Molecular Formula
- C6H2Cl2N2
- Formula Weight
- 173
- MOL File
- 1702-18-7.mol
3,6-dichloropicolinonitrile Property
- Melting point:
- 96-98 °C
- Boiling point:
- 274.5±35.0 °C(Predicted)
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- pka
- -8.16±0.10(Predicted)
- Appearance
- Off-white to yellow Solid
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D475983
- Product name
- 3,6-dichloropicolinonitrile
- Packaging
- 1g
- Price
- $240
- Updated
- 2021/12/16
- Product number
- Y5003
- Product name
- 3,6-Dichloropicolinonitrile
- Packaging
- 5g
- Price
- $251
- Updated
- 2021/12/16
- Product number
- 055400
- Product name
- 2-Cyano-3,6-dichloropyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- Y5003
- Product name
- 3,6-Dichloropicolinonitrile
- Packaging
- 1g
- Price
- $58
- Updated
- 2021/12/16
- Product number
- OR947771
- Product name
- 3,6-Dichloropicolinonitrile
- Purity
- 95%
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
3,6-dichloropicolinonitrile Chemical Properties,Usage,Production
Synthesis
53976-62-8
1702-18-7
Synthesis of 3,6-dichloro-2-cyanopyridine: 2,5-dichloropyridine-N-oxide (11.7 g, 71.38 mmol) was added batchwise to dimethyl sulfate (9 g, 71.35 mmol), followed by stirring the reaction mixture overnight. Upon completion of the reaction, 50 mL of ether was added to the mixture and stirring was continued. Subsequently, the ether layer was removed by decantation and the remaining ether was removed by distillation under vacuum. The residue was dissolved in 50 mL of water to obtain Solution A. In another vessel, sodium cyanide (13.77 g, 71.38 x 3.9 mmol) was dissolved in 67.4 mL of water and the solution was cooled under nitrogen protection to -7 °C to 15 °C. The reaction was carried out by stirring. The pre-prepared solution A was slowly added dropwise to this cooled sodium cyanide solution under continuous stirring. After the dropwise addition, the reaction temperature was kept constant and stirring was continued for 1.5 hours. At the end of the reaction, the precipitated crystal precipitate was collected by filtration and washed with water, followed by washing the solid product with a small amount of ethyl acetate. The resulting white solid had a melting point of 90-92 °C and yielded 6.6 g in 53.6% yield. The product was analyzed by IR (KBr, cm-1 ) showing characteristic absorption peaks: 2254, 1428, 1164, 840. 1H-NMR (60 MHz, CDCl3, δ) data: 7.4 (1H, d, J = 8 Hz, pyridine ring H), 7.8 (1H, d, J = 8 Hz, pyridine ring H).
References
[1] Patent: US6610853, 2003, B1
[2] Patent: US6159901, 2000, A
[3] Patent: US6200933, 2001, B1
3,6-dichloropicolinonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,6-dichloropicolinonitrile manufacturers
- Product
- 3,6-dichloropicolinonitrile 1702-18-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-08