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METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE

Product Name
METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE
CAS No.
773873-72-6
Chemical Name
METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE
Synonyms
Methyl 3;5-trifluorobenzoate;RARECHEM AL BF 0343;3,4,5-fluorobenzoate;Methyl 3,4,5-trifluorobenzoate;3,4,5-trifluoroMethyl benzoate;Methyl3,4,5-trifluorobenzoate99%;3,4,5-Trifluorobenzoic acid methyl ester;METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE;Benzoic acid, 3,4,5-trifluoro-, methyl ester
CBNumber
CB2252137
Molecular Formula
C8H5F3O2
Formula Weight
190.12
MOL File
Mol file
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METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE Property

Boiling point:
211.1±40.0 °C(Predicted)
Density 
1.358±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
liquid
color 
Clear, colourless
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
044939
Product name
Methyl 3,4,5-trifluorobenzenecarboxylate
Packaging
100.00g
Price
$48
Updated
2026/05/18
Matrix Scientific
Product number
044939
Product name
Methyl 3,4,5-trifluorobenzenecarboxylate
Packaging
500.00g
Price
$220
Updated
2026/05/18
Synthonix
Product number
M47787
Product name
Methyl 3,4,5-trifluorobenzoate
Purity
98%
Packaging
1g
Price
$14
Updated
2026/05/06
Synthonix
Product number
M47787
Product name
Methyl 3,4,5-trifluorobenzoate
Purity
98%
Packaging
5g
Price
$20
Updated
2026/05/06
Synthonix
Product number
M47787
Product name
Methyl 3,4,5-trifluorobenzoate
Purity
98%
Packaging
10g
Price
$25
Updated
2026/05/06
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METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE Chemical Properties,Usage,Production

Synthesis

67-56-1

121602-93-5

773873-72-6

Thionyl chloride (0.61 mL) was slowly added to methanol (20 mL) and the reaction mixture was stirred for 5 minutes under ice bath cooling. Subsequently, 3,4,5-trifluorobenzoic acid (1.00 g) was added in batches under the same cooling conditions, and the temperature was gradually raised to 60 °C after the addition was completed. The reaction was kept at this temperature with continuous stirring for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and subsequently concentrated under reduced pressure to remove the solvent. The resulting residue was purified by silica gel column chromatography (eluent: ethyl acetate/hexane mixed solvent) to afford the target product methyl 3,4,5-trifluorobenzoate (712 mg) as a colorless oil.

References

[1] Patent: WO2018/140809, 2018, A1. Location in patent: Paragraph 00463
[2] Patent: JP2016/141632, 2016, A. Location in patent: Paragraph 0516; 0518

METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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Energy Chemical
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China
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Accela ChemBio Co.,Ltd.
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Shandong Xiya Chemical Co., Ltd
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Bide Pharmatech Ltd.
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China
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773873-72-6, METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATERelated Search:


  • RARECHEM AL BF 0343
  • METHYL 3,4,5-TRIFLUOROBENZENECARBOXYLATE
  • Methyl 3,4,5-trifluorobenzoate
  • 5-trifluorobenzoate
  • Methyl 3
  • 3,4,5-trifluoroMethyl benzoate
  • 3,4,5-Trifluorobenzoic acid methyl ester
  • Methyl3,4,5-trifluorobenzoate99%
  • 3,4,5-fluorobenzoate
  • Benzoic acid, 3,4,5-trifluoro-, methyl ester
  • 773873-72-6