5-benzoylaminoindole

Product Name: 5-benzoylaminoindole
CAS No.: 6019-39-2
Chemical Name: 5-benzoylaminoindole
Synonyms: OAC2;CS-2128;OAC2?, >98%;OAC-2;OAC 2;OAC2 ，S5915;OAC2, 10 mM in DMSO;5-benzoylaminoindole;N-(1H-Indol-5-yl)benzaMide;Benzamide, N-1H-indol-5-yl-
CBNumber: CB22523495
Molecular Formula: C15H12N2O
Formula Weight: 236.27
MOL File: 6019-39-2.mol

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5-benzoylaminoindole Property

Melting point:: 165 - 167°C
Boiling point:: 364.3±15.0 °C(Predicted)
Density: 1.307±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 13.99±0.43(Predicted)
form: Solid
color: Pale Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1650
Product name: OAC2
Purity: ≥97% (HPLC)
Packaging: 5 mg
Price: $70.6
Updated: 2025/07/31

TCI Chemical

Product number: O0619
Product name: OAC-2
Packaging: 25MG
Price: $181
Updated: 2025/07/31

Cayman Chemical

Product number: 14103
Product name: OAC2
Purity: ≥98%
Packaging: 5mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 14103
Product name: OAC2
Purity: ≥98%
Packaging: 10mg
Price: $84
Updated: 2024/03/01

Cayman Chemical

Product number: 14103
Product name: OAC2
Purity: ≥98%
Packaging: 50mg
Price: $341
Updated: 2024/03/01

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5-benzoylaminoindole Chemical Properties,Usage,Production

Description

Octamer-binding transcription factor 4 (Oct4) is a transcription factor which, with Sox2, Klf4, and c-Myc, is involved in the reprogramming of somatic cells to produce pluripotent stem cells. OAC2 is an Oct4-activating compound which activates expression through the Oct4 gene promoter. In cells expressing Oct4 with Sox2, Klf4, and c-Myc, OAC2 (1 μM) enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibroblasts. The iPSCs developed using OAC2 retain the capacity for pluripotent differentiation, whether evaluated in vitro or in vivo.

Uses

N-(1H-Indol-5-yl)benzamide is a octamer-binding transcription factor 4 activating compound that activated Oct4 and Nanog promoters, which are essential regulators of embryonic stem cell (ESC) pluripotency and key to the reprogramming process.

References

[1] HITOSHI NIWA Austin G S Jun ichi Miyazaki. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells[J]. Nature genetics, 2000, 24 4: 372-376. DOI: 10.1038/74199
[2] KAZUTOSHI TAKAHASHI. Induction of pluripotent stem cells from adult human fibroblasts by defined factors.[J]. Cell, 2007, 131 5: 861-872. DOI: 10.1016/j.cell.2007.11.019
[3] WENDONG LI. Identification of Oct4-activating compounds that enhance reprogramming efficiency.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2012: 20853-20858. DOI: 10.1073/pnas.1219181110

5-benzoylaminoindole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-benzoylaminoindole manufacturers

Career Henan Chemical Co

Product: 5-benzoylaminoindole 6019-39-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%~99%
Supply Ability: per week 100kg
Release date: 2019-09-05

6019-39-2, 5-benzoylaminoindoleRelated Search:

5-benzoylaminoindole

N-(1H-Indol-5-yl)benzaMide

OAC2

CS-2128

OAC-2;OAC 2

OAC2?, >98%

Benzamide, N-1H-indol-5-yl-

OAC2, 10 mM in DMSO

OAC2 ，S5915

6019-39-2

Inhibitors

Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals