Furo[3,2-b]pyridine, 7-chloro-
- Product Name
- Furo[3,2-b]pyridine, 7-chloro-
- CAS No.
- 182691-75-4
- Chemical Name
- Furo[3,2-b]pyridine, 7-chloro-
- Synonyms
- 7-Chloro-furo[3,2-b]pyridine;7-Chloro-furo[3,2-b]pyrid...;Furo[3,2-b]pyridine, 7-chloro-
- CBNumber
- CB22525101
- Molecular Formula
- C7H4ClNO
- Formula Weight
- 153.57
- MOL File
- 182691-75-4.mol
Furo[3,2-b]pyridine, 7-chloro- Property
- Boiling point:
- 204.3±20.0 °C(Predicted)
- Density
- 1.377±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 2.53±0.30(Predicted)
- Appearance
- brown solid
- InChI
- InChI=1S/C7H4ClNO/c8-5-1-3-9-6-2-4-10-7(5)6/h1-4H
- InChIKey
- JVRFEXMVMBMREK-UHFFFAOYSA-N
- SMILES
- C12C=COC1=C(Cl)C=CN=2
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C373683
- Product name
- 7-Chlorofuro[3,2-b]pyridine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C373683
- Product name
- 7-Chlorofuro[3,2-b]pyridine
- Packaging
- 50mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 4H56-5-1N
- Product name
- 7-Chlorofuro[3,2-b]pyridine
- Packaging
- 250mg
- Price
- $425
- Updated
- 2021/12/16
- Product number
- 068800
- Product name
- 7-Chlorofuro[3,2-b]pyridine
- Purity
- >95%
- Packaging
- 100mg
- Price
- $530
- Updated
- 2021/12/16
- Product number
- 068800
- Product name
- 7-Chlorofuro[3,2-b]pyridine
- Purity
- >95%
- Packaging
- 500mg
- Price
- $1571
- Updated
- 2021/12/16
Furo[3,2-b]pyridine, 7-chloro- Chemical Properties,Usage,Production
Synthesis
1071540-51-6
182691-75-4
General procedure for the synthesis of 7-chlorofuro[3,2-b]pyridines from 2-(trimethylsilyl)-7-chlorofuro[3,2-B]pyridines: to a solution of compound 2-(trimethylsilyl)-7-chlorofuro[3,2-B]pyridine (73 g, 0.323 mol, 1.0 eq.) in tetrahydrofuran (THF, 400 mL) was added an aqueous sodium hydroxide solution ( 300 mL, 4 mol/L). The reaction mixture was stirred at 50 °C for 1 h and then cooled to room temperature and 1000 mL of water was added. The mixture was extracted twice with methyl tert-butyl ether (MTBE). The combined organic layers were washed with saturated saline, dried over anhydrous sodium sulfate, concentrated, and recrystallized from a solvent mixture of ethyl acetate and petroleum ether to give 7-chlorofuro[3,2-b]pyridine as an off-white powder (30 g, 60.5% yield).GC-MS analysis showed the molecular ion peak as 153 (EI).
References
[1] Patent: WO2018/67422, 2018, A1. Location in patent: Page/Page column 38; 40
Furo[3,2-b]pyridine, 7-chloro- Preparation Products And Raw materials
Raw materials
Preparation Products
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