3-Fluoro-4-nitrobenzyl alcohol 99%
- Product Name
- 3-Fluoro-4-nitrobenzyl alcohol 99%
- CAS No.
- 503315-74-0
- Chemical Name
- 3-Fluoro-4-nitrobenzyl alcohol 99%
- Synonyms
- Structure;(3-Fluoro-4-nitrophenyl);3-Fluoro-4-nitrobenzenemethanol;3-Fluoro-4-nitrobenzylalcohol98%;Benzenemethanol, 3-fluoro-4-nitro-;3-Fluoro-4-nitrobenzyl alcohol 99%;3-Fluoro-4-nitrobenzyl alcohol 99%;3-Fluoro-4-nitrobenzyl alcohol, 96% (Cu;(3-Fluoro-4-nitrophenyl)methanol, 2-Fluoro-4-(hydroxymethyl)nitrobenzene
- CBNumber
- CB22527963
- Molecular Formula
- C7H6FNO3
- Formula Weight
- 171.13
- MOL File
- 503315-74-0.mol
3-Fluoro-4-nitrobenzyl alcohol 99% Property
- Boiling point:
- 328.6±27.0 °C(Predicted)
- Density
- 1.434
- storage temp.
- Sealed in dry,Room Temperature
- form
- Solid
- pka
- 13.27±0.10(Predicted)
- Appearance
- Off-white to light yellow Solid
Safety
- HS Code
- 2906290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P281Use personal protective equipment as required.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313IF exposed or concerned: Get medical advice/attention.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- F597663
- Product name
- (3-Fluoro-4-nitro-phenyl)-methanol
- Packaging
- 500mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 4654-3-51
- Product name
- 3-Fluoro-4-nitrobenzyl alcohol
- Purity
- 98%
- Packaging
- 1g
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 047014
- Product name
- (3-Fluoro-4-nitrophenyl)methanol
- Purity
- >95%
- Packaging
- 500mg
- Price
- $58
- Updated
- 2021/12/16
- Product number
- V6240
- Product name
- (3-Fluoro-4-nitrophenyl)methanol
- Packaging
- 1g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- PC4403
- Product name
- 3-Fluoro-4-nitrobenzylalcohol
- Purity
- 98%
- Packaging
- 1g
- Price
- $86
- Updated
- 2021/12/16
3-Fluoro-4-nitrobenzyl alcohol 99% Chemical Properties,Usage,Production
Synthesis
403-21-4
503315-74-0
Part A. Preparation of (3-fluoro-4-nitrophenyl)methanol. To a solution of 3-fluoro-4-nitrobenzoic acid (2.0 g, 10.8 mmol) in tetrahydrofuran (THF, 50 ml) was added dropwise borane-dimethyl sulfide complex (BH3-Me2S, 2.215 ml, 22.15 mmol) at 0 °C. The reaction mixture was stirred at 0 °C for 3 h, followed by warming up to 65 °C and continued stirring for 18 h. The reaction was carried out at 0 °C. Upon completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched by the slow addition of ice (50 g) followed by the addition of 1 M aqueous hydrochloric acid solution (100 ml). The reaction mixture was extracted with ethyl acetate (EtOAc, 200 ml), the organic layers were combined, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to give the title compound (3-fluoro-4-nitrophenyl)methanol as a white solid (1.79 g, 97% yield).
References
[1] Patent: WO2009/39135, 2009, A1. Location in patent: Page/Page column 140
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 3, p. 1153 - 1163
[3] Patent: WO2011/66416, 2011, A1. Location in patent: Page/Page column 16
[4] Patent: WO2004/7491, 2004, A1. Location in patent: Page 65
[5] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 13, p. 3986 - 3991
3-Fluoro-4-nitrobenzyl alcohol 99% Preparation Products And Raw materials
Raw materials
Preparation Products
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