ChemicalBook > CAS DataBase List > PF 184

PF 184

Product Name
PF 184
CAS No.
1187460-81-6
Chemical Name
PF 184
Synonyms
PF 184;8-[[[5-Chloro-2-[3,4-diMethyl-3,4-bis(hydroxyMethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]aMino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxaMide;1H-Benz[g]indazole-3-carboxamide, 8-[[[2-[3,4-bis(hydroxymethyl)-3,4-dimethyl-1-pyrrolidinyl]-5-chloro-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-
CBNumber
CB22535689
Molecular Formula
C32H32ClFN6O4
Formula Weight
619.09
MOL File
1187460-81-6.mol
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PF 184 Property

Boiling point:
790.6±60.0 °C(Predicted)
Density 
1.47±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble to 100 mM in DMSO
form 
Powder
pka
10.20±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
4238
Product name
PF184
Purity
≥98%(HPLC)
Packaging
10
Price
$331
Updated
2021/12/16
TRC
Product number
P293750
Product name
PF184
Packaging
1mg
Price
$165
Updated
2021/12/16
Usbiological
Product number
019312
Product name
PF 184
Packaging
10mg
Price
$502
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010308
Product name
8-[[[5-CHLORO-2-[3,4-DIMETHYL-3,4-BIS(HYDROXYMETHYL)-1-PYRROLIDINYL]-4-PYRIDINYL]CARBONYL]AMINO]-1-(4-FLUOROPHENYL)-4,5-DIHYDRO-1H-BENZ[G]INDAZOLE-3-CARBOXAMIDE
Purity
95.00%
Packaging
10MG
Price
$716.1
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010308
Product name
8-[[[5-CHLORO-2-[3,4-DIMETHYL-3,4-BIS(HYDROXYMETHYL)-1-PYRROLIDINYL]-4-PYRIDINYL]CARBONYL]AMINO]-1-(4-FLUOROPHENYL)-4,5-DIHYDRO-1H-BENZ[G]INDAZOLE-3-CARBOXAMIDE
Purity
95.00%
Packaging
25MG
Price
$779.63
Updated
2021/12/16
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PF 184 Chemical Properties,Usage,Production

Uses

PF 184 is a potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1β-induced TNF-α in a steroid-insensitive in vitro model of oxidative stress.

storage

Store at +4°C

PF 184 Preparation Products And Raw materials

Raw materials

Preparation Products

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PF 184 Suppliers

J & K SCIENTIFIC LTD.
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order@med-bio.cn
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marketing@tsbiochem.com
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0513-66337626 18051384581
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1187460-81-6, PF 184Related Search:


  • PF 184
  • 8-[[[5-Chloro-2-[3,4-diMethyl-3,4-bis(hydroxyMethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]aMino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxaMide
  • 1H-Benz[g]indazole-3-carboxamide, 8-[[[2-[3,4-bis(hydroxymethyl)-3,4-dimethyl-1-pyrrolidinyl]-5-chloro-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-
  • 1187460-81-6
  • C32H32ClFN6O4
  • Amines
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pfizer Compounds
  • Pharmaceuticals