ChemicalBook > CAS DataBase List > Myo-Inositol Trispyrophosphate HexasodiuM Salt
Myo-Inositol Trispyrophosphate HexasodiuM Salt
- Product Name
- Myo-Inositol Trispyrophosphate HexasodiuM Salt
- CAS No.
- 23103-35-7
- Chemical Name
- Myo-Inositol Trispyrophosphate HexasodiuM Salt
- Synonyms
- ITPP;ITTP HexasodiuM Salt;Myo-Inositol Tripyrphosphate HexasodiuM salt;Myo-Inositol Trispyrophosphate HexasodiuM Salt;Myo-Inositol Trispyrophosphate HexasodiuM Salt 9;MYO-INOSITOL TRISPYROPHOSPHATE HEXASODIUM (ITPP);Inositol cyclic-1,2:3,4:5,6-tris(P,P'-dihydrogen diphosphate) hexasodium salt;Myo-Inositol Cyclic 1,2:3,4:5,6-Tris(dihydrogen pyrophosphate)) HexasodiuM Salt;Myo-Inositol Cyclic 1,2:3,4:5,6-Tris(P,P'-dihydrogen diphosphate) HexasodiuM Salt;sodium hexahydrobenzo[1,2-f:3,4-f':5,6-f'']tris([1,3,5,2,4]trioxadiphosphepine)-2,4,7,9,12,14-hexakis(olate) 2,4,7,9,12,14-hexaoxide
- CBNumber
- CB22551061
- Molecular Formula
- C6H13NaO21P6
- Formula Weight
- 629.98
- MOL File
- 23103-35-7.mol
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Myo-Inositol Trispyrophosphate HexasodiuM Salt Property
- Melting point:
- >270°C (dec.)
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- Water (Slightly, Sonicated)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
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N-Bromosuccinimide Price
TRC
- Product number
- I666020
- Product name
- myo-InositolTrispyrophosphateHexasodiumSalt
- Packaging
- 10mg
- Price
- $185
- Updated
- 2021/12/16
Usbiological
- Product number
- 293797
- Product name
- myo-Inositol trispyrophosphate hexasodium salt
- Packaging
- 2g
- Price
- $358
- Updated
- 2021/12/16
TRC
- Product number
- I666020
- Product name
- myo-InositolTrispyrophosphateHexasodiumSalt
- Packaging
- 100mg
- Price
- $1455
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- MI16762
- Product name
- myo-Inositol trispyrophosphate hexasodium salt
- Packaging
- 25mg
- Price
- $600
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- MI16762
- Product name
- myo-Inositol trispyrophosphate hexasodium salt
- Packaging
- 10mg
- Price
- $300
- Updated
- 2021/12/16
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Myo-Inositol Trispyrophosphate HexasodiuM Salt Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
A novel membrane-permeant allosteric effector of hemoglobin (Hb), enhances the regulated oxygen release capacity of red blood cells, thus counteracting the effects of hypoxia in diseases such as cancer and cardiovascular ailments.
in vivo
Non-salt dose:
myo-Inositol trispyrophosphate (1.5 g/kg; intraperitoneal injection; twice a week for 4 weeks) has a protective effect in rat model of myocardial infarction[1].
myo-Inositol trispyrophosphate (1.5 g/kg; intravenous injection; once a week for 11 weeks) has antitumor activity in a rat model of pancreatic cancer[2].
| Animal Model: | Male Wistar rats (280-320 g) with myocardial infarction[1] |
| Dosage: | 1.5 g/kg (Non-salt dose) |
| Administration: | Intraperitoneal injection (i.p.); twice a week for 4 weeks |
| Result: | Essentially halted the increase of LV dilation and significantly reduced impairment of LV ejection fraction, while it had no effect on sham-operated rats. |
| Animal Model: | DSL-6A/C1 tumors treated immunocompetent male Lewis rats[2] |
| Dosage: | 1.5 g/kg (Non-salt dose) |
| Administration: | Intravenous injection (i.v.); once a week for 11 weeks |
| Result: | Significantly extended the survival time of rats. Basically did not cause liver metastasis and primary tumor growth was restricted to 2 cm3. Restored the pO2 pressure in tumors reducing hypoxia-inducible and proangiogenic factors. |
Myo-Inositol Trispyrophosphate HexasodiuM Salt Preparation Products And Raw materials
Raw materials
Preparation Products
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Myo-Inositol Trispyrophosphate HexasodiuM Salt Suppliers
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