ChemicalBook > CAS DataBase List > 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
- Product Name
- 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
- CAS No.
- 1363380-51-1
- Chemical Name
- 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
- Synonyms
- arotrectinib CNPP Impurity;Larotrectinib CNPP Impurity;5-Chloro-3-nitropyrazolo[...;Chloro-3-nitropyrazolo[1,5-a]pyrimidine;5-Chloro-3-nitropyrazolo[1,5-a]pyriMidin;5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine;5-chloro-3-nitropyrazole [1,5-a] pyrimidine;Pyrazolo[1,5-a]pyrimidine, 5-chloro-3-nitro-;5-chloro-3-nitropyrazolo[1,5-a]pyrimidine (Nitro );Larotrectinib Impurity 1(Larotrectinib CNPP Impurity)
- CBNumber
- CB22582618
- Molecular Formula
- C6H3ClN4O2
- Formula Weight
- 198.57
- MOL File
- 1363380-51-1.mol
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5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Property
- Melting point:
- 163 - 165°C
- Density
- 1.85±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- Chloroform (Slightly, Heated), DMSO (Slightly)
- form
- Solid
- pka
- -3.59±0.40(Predicted)
- color
- Purple
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Safety
- HS Code
- 2933998090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TRC
- Product number
- C371555
- Product name
- 5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine
- Packaging
- 250mg
- Price
- $130
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-M3730
- Product name
- Pyrazolo[1,5-a]pyrimidine,5-chloro-3-nitro-
- Purity
- 97.75%
- Packaging
- 5g
- Price
- $141
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-M3730
- Product name
- Pyrazolo[1,5-a]pyrimidine,5-chloro-3-nitro-
- Purity
- 97.75%
- Packaging
- 1g
- Price
- $33
- Updated
- 2021/12/16
Apolloscientific
- Product number
- OR52568
- Product name
- 5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine
- Purity
- 97%
- Packaging
- 5g
- Price
- $219
- Updated
- 2021/12/16
AK Scientific
- Product number
- 0771DW
- Product name
- 5-Chloro-3-nitropyrazolo[1,5-A]pyrimidine
- Packaging
- 5g
- Price
- $228
- Updated
- 2021/12/16
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5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Chemical Properties,Usage,Production
Uses
5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine is used in the preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, a tyrosine kinase (TRK) inhibitor for treating cancer.
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine manufacturers
Nanjing Fred Technology Co., Ltd
- Product
- 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine 1363380-51-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-26
Henan Fengda Chemical Co., Ltd
- Product
- 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine 1363380-51-1
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-10
Hebei Yanxi Chemical Co., Ltd.
- Product
- 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine 1363380-51-1
- Price
- US $40.00-40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-07