ChemicalBook > CAS DataBase List > 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine

5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine

Product Name
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
CAS No.
1363380-51-1
Chemical Name
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine
Synonyms
arotrectinib CNPP Impurity;Larotrectinib CNPP Impurity;5-Chloro-3-nitropyrazolo[...;Chloro-3-nitropyrazolo[1,5-a]pyrimidine;5-Chloro-3-nitropyrazolo[1,5-a]pyriMidin;5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine;5-chloro-3-nitropyrazole [1,5-a] pyrimidine;Pyrazolo[1,5-a]pyrimidine, 5-chloro-3-nitro-;5-chloro-3-nitropyrazolo[1,5-a]pyrimidine (Nitro );Larotrectinib Impurity 1（Larotrectinib CNPP Impurity）
CBNumber
CB22582618
Molecular Formula
C6H3ClN4O2
Formula Weight
198.57
MOL File
1363380-51-1.mol
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5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Property

Melting point:
163 - 165°C
Density 
1.85±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly)
form 
Solid
pka
-3.59±0.40(Predicted)
color 
Purple
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C371555
Product name
5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine
Packaging
250mg
Price
$130
Updated
2021/12/16
ChemScene
Product number
CS-M3730
Product name
Pyrazolo[1,5-a]pyrimidine,5-chloro-3-nitro-
Purity
97.75%
Packaging
5g
Price
$141
Updated
2021/12/16
ChemScene
Product number
CS-M3730
Product name
Pyrazolo[1,5-a]pyrimidine,5-chloro-3-nitro-
Purity
97.75%
Packaging
1g
Price
$33
Updated
2021/12/16
Apolloscientific
Product number
OR52568
Product name
5-Chloro-3-nitropyrazolo[1,5-a]pyrimidine
Purity
97%
Packaging
5g
Price
$219
Updated
2021/12/16
AK Scientific
Product number
0771DW
Product name
5-Chloro-3-nitropyrazolo[1,5-A]pyrimidine
Packaging
5g
Price
$228
Updated
2021/12/16
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5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Chemical Properties,Usage,Production

Uses

5-Chloro-3-nitro-pyrazolo[1,5-a]pyrimidine is used in the preparation of (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide, a tyrosine kinase (TRK) inhibitor for treating cancer.

5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine Suppliers

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View Lastest Price from 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine manufacturers

Nanjing Fred Technology Co., Ltd
Product
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine 1363380-51-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-26
Hebei Yanxi Chemical Co., Ltd.
Product
5-Chloro-3-nitropyrazolo[1,5-a]pyriMidine 1363380-51-1
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-07
Hebei Kingfiner Technology Development Co.Ltd
Product
5-chloro-3-nitropyrazole [1,5-a] pyrimidine 1363380-51-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000kg
Release date
2023-12-05

1363380-51-1, 5-Chloro-3-nitropyrazolo[1,5-a]pyriMidineRelated Search:

Pyrazole

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