TG100801

ChemicalBook > CAS DataBase List > TG100801

Product Name: TG100801
CAS No.: 867331-82-6
Chemical Name: TG100801
Synonyms: TG100801;TG100801;TG-100801;4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-amino)benzo[e][1,2,4]triazin-7-y;4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-amino)benzo[e][1,2,4]triazin-7-yl)p;4-Chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)benzo[e][1,2,4]triazin-7-yl)phenyl benzoate;4-Chloro-3-[5-methyl-3-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-1,2,4-benzotriazin-7-yl]phenol 1-benzoate;Phenol, 4-chloro-3-[5-Methyl-3-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]aMino]-1,2,4-benzotriazin-7-yl]-, 1-benzoate
CBNumber: CB22583019
Molecular Formula: C33H30ClN5O3
Formula Weight: 580.08
MOL File: 867331-82-6.mol

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TG100801 Property

Boiling point:: 747.9±70.0 °C(Predicted)
Density: 1.310
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
pka: 9.59±0.20(Predicted)
color: Brown to reddish brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0785
Product name: TG100801
Purity: 98.60%
Packaging: 5mg
Price: $264
Updated: 2021/12/16

ApexBio Technology

Product number: A3870
Product name: TG100801
Packaging: 5mg
Price: $322
Updated: 2021/12/16

ChemScene

Product number: CS-0785
Product name: TG100801
Purity: 98.60%
Packaging: 10mg
Price: $456
Updated: 2021/12/16

ApexBio Technology

Product number: A3870
Product name: TG100801
Packaging: 10mg
Price: $557
Updated: 2021/12/16

Matrix Scientific

Product number: 098186
Product name: 4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-amino)benzo[e][1,2,4]triazin-7-yl)phenyl benzoate
Purity: 95+%
Packaging: 250mg
Price: $742
Updated: 2021/12/16

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TG100801 Chemical Properties,Usage,Production

Biological Activity

tg100801 is a multi-kinases inhibitor. it is a pro-drug version of tg100572. [1]tg100572 inhibits several growth factor receptors in addition to src family kinases. tg100801 significantly inhibited laser-induced cnv in mice, and suppressed fluorescein leakage from the vasculature and retinal thickening measured by optical coherence tomography in a rat model or retinal vein occlusion. tg100801 may play as a new topically applied treatment approach for ocular neovascularization and retinal edema. the highest concentration of tg100801 was found at the front of the rat eye (conjunctiva and cornea). [1]

target

VEGFR1

References

1. doukas j, mahesh s, umeda n et al. topical administration of a multi-targeted kinase inhibitor suppresses choroidal neovascularization and retinal edema. j cell physiol. 2008 jul;216(1):29-37.

TG100801 Preparation Products And Raw materials

Raw materials

Preparation Products

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867331-82-6, TG100801Related Search:

TG100801

Phenol, 4-chloro-3-[5-Methyl-3-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]aMino]-1,2,4-benzotriazin-7-yl]-, 1-benzoate

4-Chloro-3-[5-methyl-3-[[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]amino]-1,2,4-benzotriazin-7-yl]phenol 1-benzoate

4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-amino)benzo[e][1,2,4]triazin-7-yl)p

4-Chloro-3-(5-methyl-3-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)benzo[e][1,2,4]triazin-7-yl)phenyl benzoate

4-Chloro-3-(5-methyl-3-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-amino)benzo[e][1,2,4]triazin-7-y

TG100801;TG-100801

867331-82-6

C33H30ClN5O3