ChemicalBook > CAS DataBase List > GTP-GAMMA-S SODIUM SALT

GTP-GAMMA-S SODIUM SALT

Product Name
GTP-GAMMA-S SODIUM SALT
CAS No.
37589-80-3
Chemical Name
GTP-GAMMA-S SODIUM SALT
Synonyms
GTP-γ-S;GTP-GAMMA-S;GTP-GAMMA-S, NA;GTP-GAMMA-S SODIUM SALT;guanosine5’-o-(3-thiotriphosphate;Guanosine 5'-γ-thiotriphosphoric acid;Guanosine 5'-(γ-thiotriphosphoric acid);Guanosine 5'-O-(γ-thiotriphosphoric acid);5'-Guanylyloxyphosphonyloxythiophosphonic acid;GUANOSINE-5'-O-(3-THIOTRIPHOSPHATE) SODIUM SALT
CBNumber
CB2260156
Molecular Formula
C10H16N5O13P3S
Formula Weight
539.25
MOL File
37589-80-3.mol
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GTP-GAMMA-S SODIUM SALT Property

Density 
2.68±0.1 g/cm3(Predicted)
storage temp. 
-20°C (-15°C to -25°C)
pka
0.67±0.50(Predicted)
form 
solution (deep frozen)
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Safety

WGK Germany 
-
F 
10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
10220647001
Product name
GTP-γ-S
Purity
Tetralithium salt
Packaging
10MG
Price
$346
Updated
2022/05/15
American Custom Chemicals Corporation
Product number
NUC0004604
Product name
GTP-GAMMA-S SODIUM SALT
Purity
95.00%
Packaging
5MG
Price
$497.06
Updated
2021/12/16
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GTP-GAMMA-S SODIUM SALT Chemical Properties,Usage,Production

Uses

GTP-γ-S has been used:

  • in G-Protein activation assay to assess the functionality of protease-activated receptor 4 (PAR4)
  • in fluorimetric guanine nucleotide exchange assay of G protein alpha subunits (Gα)
  • to monitor the Rac family small guanosine triphosphatase (GTPase) 2 (Rac2)-stimulated activity of phospholipase Cγ2 mutants

Definition

ChEBI: Guanosine 5'-[gamma-thio]triphosphate is a nucleoside triphosphate analogue. It is functionally related to a GTP.

General Description

Guanosine 5′-O-(3-thiotriphosphate), tetralithium salt (GTP-γ-S) is a non-hydrolysable analog of GTP. It is an inhibitor of phosphodiesterase in photoreceptors.

Biochem/physiol Actions

Guanosine 5′-O-(3-thiotriphosphate) (GTP-γ-S) activates guanine-nucleotide-binding proteins and is slowly hydrolyzed enzymatically. It inhibits guanosine triphosphatase (GTPases) more potently than guanosine triphosphate (GTP),

GTP-GAMMA-S SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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GTP-GAMMA-S SODIUM SALT Suppliers

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37589-80-3, GTP-GAMMA-S SODIUM SALTRelated Search:

GTP GTP-GAMMA-S SODIUM SALT

  • GTP-GAMMA-S
  • GTP-GAMMA-S, NA
  • GTP-GAMMA-S SODIUM SALT
  • GUANOSINE-5'-(GAMMA-THIO)-TRIPHOSPHATE, SODIUM SALT
  • GUANOSINE-5'-[GAMMA-THIO]TRIPHOSPHATE TETRASODIUM SALT
  • GUANOSINE-5'-O-(3-THIOTRIPHOSPHATE) SODIUM SALT
  • GUANOSINE-5'-O-(3-THIOTRIPHOSPHORIC ACID), SODIUM
  • GTP-γ-S
  • Guanosine-5μ-[γ-thio]triphosphate solution tetrasodium salt
  • guanosine5’-o-(3-thiotriphosphate
  • guanosine-5’-o-(3-thiotriphosphate),(gtp-g-s),sodiumsalt
  • 5'-Guanylyloxyphosphonyloxythiophosphonic acid
  • Guanosine 5'-(γ-thiotriphosphoric acid)
  • Guanosine 5'-O-(γ-thiotriphosphoric acid)
  • Guanosine 5'-γ-thiotriphosphoric acid
  • Guanosine5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid
  • Guanosine-5′-[γ-thio]triphosphate tetrasodium salt solution
  • 37589-80-3
  • C10H12N5Na4O13P3S