1H-Pyrrolo[2,3-b]pyridine, 5-broMo-3-nitro-
- Product Name
- 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-3-nitro-
- CAS No.
- 507462-26-2
- Chemical Name
- 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-3-nitro-
- Synonyms
- 5-BroMo-3-nitro-7-azaindole;5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine;1H-Pyrrolo[2,3-b]pyridine, 5-broMo-3-nitro-;5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine
- CBNumber
- CB22625610
- Molecular Formula
- C7H4BrN3O2
- Formula Weight
- 242.03
- MOL File
- 507462-26-2.mol
1H-Pyrrolo[2,3-b]pyridine, 5-broMo-3-nitro- Property
- Density
- 1.965±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 9.88±0.40(Predicted)
- form
- solid
- Appearance
- Yellow to khaki Solid
- InChI
- 1S/C7H4BrN3O2/c8-4-1-5-6(11(12)13)3-10-7(5)9-2-4/h1-3H,(H,9,10)
- InChIKey
- GHHWPSOGKLMSCJ-UHFFFAOYSA-N
- SMILES
- [O-][N+](=O)c1c[nH]c2ncc(Br)cc12
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SYX00270
- Product name
- 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $276
- Updated
- 2026/03/19
- Product number
- B686573
- Product name
- 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 115760
- Product name
- 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine
- Purity
- 95%
- Packaging
- 1g
- Price
- $269
- Updated
- 2021/12/16
- Product number
- 115760
- Product name
- 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine
- Purity
- 95%
- Packaging
- 5g
- Price
- $1143
- Updated
- 2021/12/16
- Product number
- 115760
- Product name
- 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine
- Purity
- 95%
- Packaging
- 25g
- Price
- $4410
- Updated
- 2021/12/16
1H-Pyrrolo[2,3-b]pyridine, 5-broMo-3-nitro- Chemical Properties,Usage,Production
Synthesis
183208-35-7
507462-26-2
General procedure for the synthesis of 5-bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine from 5-bromo-7-azaindole: 5-bromo-1H-pyrrolo[2,3-b]pyridine (470 mg, 2.39 mmol) was added to stirred fuming nitric acid (2.5 mL) in batches at 0 °C. After the addition was completed, the reaction system was kept at 0 °C and stirring was continued for 30 min. Subsequently, the reaction solution was carefully poured into an ice-water mixture (25 mL) and stirred for 30 min. The solid product was isolated by filtration, and the filter cake was washed sequentially with a large amount of deionized water and isohexane, and finally dried under vacuum to afford the target compound 5-bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine (484 mg, 84% yield).
References
[1] Patent: WO2013/114113, 2013, A1. Location in patent: Page/Page column 23
[2] Patent: US2015/11533, 2015, A1. Location in patent: Paragraph 0101
[3] Patent: WO2018/134254, 2018, A1. Location in patent: Page/Page column 78; 79
1H-Pyrrolo[2,3-b]pyridine, 5-broMo-3-nitro- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1H-Pyrrolo[2,3-b]pyridine, 5-broMo-3-nitro- manufacturers
- Product
- 5-Bromo-3-nitro-1H-pyrrolo[2,3-b]pyridine 507462-26-2
- Price
- US $1.60-6.60/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-19