ChemicalBook > CAS DataBase List > ABT 894
ABT 894
- Product Name
- ABT 894
- CAS No.
- 799279-80-4
- Chemical Name
- ABT 894
- Synonyms
- ABT 894;Sofiniclin;A 422894.0;Sofinicline;ABT-894; ABT 894; ABT894;3,6-Diazabicyclo[3.2.0]heptane, 3-(5,6-dichloro-3-pyridinyl)-, (1S,5S)-
- CBNumber
- CB22627245
- Molecular Formula
- C10H11Cl2N3
- Formula Weight
- 244.12
- MOL File
- 799279-80-4.mol
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ABT 894 Property
- Boiling point:
- 417.4±45.0 °C(Predicted)
- Density
- 1.406±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 10.31±0.20(Predicted)
- color
- Off-white to brown
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- KIN0001099
- Product name
- ABT-894
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $186.9
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6792
- Product name
- Sofiniclin
- Purity
- 95.98%
- Packaging
- 1mg
- Price
- $432
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6792
- Product name
- Sofiniclin
- Purity
- 95.98%
- Packaging
- 5mg
- Price
- $864
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-6792
- Product name
- Sofiniclin
- Purity
- 95.98%
- Packaging
- 10mg
- Price
- $1596
- Updated
- 2021/12/16
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ABT 894 Chemical Properties,Usage,Production
Biological Activity
Sofiniclin (ABT 894) is an agonist of nAChR as a potential non-stimulatory study in attention deficit disorder.
in vitro
ABT 894 is more potent than ABT-089 at both receptor subtypes, with K i values of 1.9 nM for 125 I-α-conotoxinMII binding and of 1.3 nM for 125 I-epibatidine binding.
in vivo
ABT 894 (0.001 to 0.10 mg/kg, po) produces significant reductions in LIDs compared to vehicle monkey. It does not decrease LIDs in monkeys with severe nigrostriatal damage.
< p>ABT 894 Preparation Products And Raw materials
Raw materials
Preparation Products
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