ChemicalBook > CAS DataBase List > LUF 6000

LUF 6000

Product Name
LUF 6000
CAS No.
890087-21-5
Chemical Name
LUF 6000
Synonyms
LUF 6000;LUF-6000;LUF 6000;2-Cyclohexyl-N-(3,4-dichlorophenyl)-1H-imidazo[4,5-c]quinolin-4-amine;N-(3,4-Dichlorophenyl)-2-cyclohexyl-1H-imidazo[4,5-c]quinolin-4-amine;3H-Imidazo[4,5-c]quinolin-4-amine, 2-cyclohexyl-N-(3,4-dichlorophenyl)-
CBNumber
CB22628055
Molecular Formula
C22H20Cl2N4
Formula Weight
411.33
MOL File
890087-21-5.mol
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LUF 6000 Property

Melting point:
237-240℃ (methanol water )
Boiling point:
650.5±55.0 °C(Predicted)
Density 
1.401±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 14.29 mg/mL (34.74 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
Powder
pka
12.13±0.40(Predicted)
color 
Light brown to brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28437
Product name
LUF6000
Packaging
500μg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
28437
Product name
LUF6000
Packaging
5mg
Price
$711
Updated
2024/03/01
Cayman Chemical
Product number
28437
Product name
LUF6000
Packaging
1mg
Price
$152
Updated
2024/03/01
AK Scientific
Product number
0057CT
Product name
2-Cyclohexyl-N-(3,4-dichlorophenyl)-3H-imidazo[4,5-c]quinolin-4-amine
Packaging
1mg
Price
$267
Updated
2021/12/16
ChemScene
Product number
CS-1158
Product name
LUF6000
Purity
99.57%
Packaging
5mg
Price
$396
Updated
2021/12/16
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LUF 6000 Chemical Properties,Usage,Production

Uses

LUF6000 is an orally active allosteric modulator of the A3 adenosine receptor. LUF6000 has potent anti-inflammatory effect[1][2].

in vivo

LUF6000 induces anti-inflammatory effect in 3 experimental animal models of rat adjuvant induced arthritis, monoiodoacetate induced osteoarthritis, and concanavalin A induced liver inflammation in mice[2].

References

[1] Du L, et al. Species differences and mechanism of action of A3 adenosine receptor allosteric modulators. Purinergic Signal. 2018;14(1):59-71. DOI:10.1007/s11302-017-9592-1
[2] Cohen S, et al. A? adenosine receptor allosteric modulator induces an anti-inflammatory effect: in vivo studies and molecular mechanism of action. Mediators Inflamm. 2014;2014:708746. DOI:10.1155/2014/708746

LUF 6000 Preparation Products And Raw materials

Raw materials

Preparation Products

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LUF 6000 Suppliers

China 43 United States 6 Global 49
Haoyuan Chemexpress Co., Ltd.
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890087-21-5, LUF 6000Related Search:


  • LUF 6000
  • N-(3,4-Dichlorophenyl)-2-cyclohexyl-1H-imidazo[4,5-c]quinolin-4-amine
  • 2-Cyclohexyl-N-(3,4-dichlorophenyl)-1H-imidazo[4,5-c]quinolin-4-amine
  • LUF-6000;LUF 6000
  • 3H-Imidazo[4,5-c]quinolin-4-amine, 2-cyclohexyl-N-(3,4-dichlorophenyl)-
  • 890087-21-5
  • C22H20Cl2N4