Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate
- Product Name
- Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate
- CAS No.
- 319442-19-8
- Chemical Name
- Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate
- Synonyms
- ethyl 4-oxo-4aH-thieno[3,2-d]pyrimidine-2-carboxylate;Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate;Thieno[3,2-d]pyrimidine-2-carboxylic acid, 3,4-dihydro-4-oxo-, ethyl ester
- CBNumber
- CB22650856
- Molecular Formula
- C9H8N2O3S
- Formula Weight
- 224.24
- MOL File
- 319442-19-8.mol
Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Property
- storage temp.
- 2-8°C(protect from light)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- Z4589
- Product name
- Ethyl4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-2-carboxylate
- Packaging
- 250mg
- Price
- $146
- Updated
- 2021/12/16
- Product number
- Z4589
- Product name
- Ethyl4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-2-carboxylate
- Packaging
- 1g
- Price
- $290
- Updated
- 2021/12/16
- Product number
- CHM0392531
- Product name
- ETHYL-4-OXO-3,4-DIHYDROTHIENO[3,2-D]PYRIMIDINE-2-CARBOXYLATE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.07
- Updated
- 2021/12/16
- Product number
- CM165216
- Product name
- Ethyl4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-2-carboxylate
- Purity
- 98%
- Packaging
- 5g
- Price
- $502
- Updated
- 2021/12/16
- Product number
- CD11146080
- Product name
- Ethyl4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-2-carboxylate
- Purity
- 98%
- Packaging
- 5g
- Price
- $532
- Updated
- 2021/12/16
Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Chemical Properties,Usage,Production
Synthesis
22288-78-4
623-49-4
319442-19-8
Step A: Methyl 3-amino-2-thiophenecarboxylate (3.0 g, 19 mmol) was dissolved in acetic acid (24 mL), followed by the sequential addition of concentrated hydrochloric acid (2.4 mL) and ethyl cyanoformate (3.78 g, 38 mmol). The resulting inhomogeneous mixture was heated and stirred at 70 °C for 3 h. After completion of the reaction, it was cooled to room temperature. The solid generated in the reaction was collected by filtration and washed with deionized water. The filtrate was adjusted to a pH of about 5 with 1N NaOH solution, at which point a solid precipitated, and the precipitate was collected by filtration and again washed with deionized water. The two collected solids were combined and dried overnight in a vacuum drying oven to give the final ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyrimidine-2-carboxylate (2.69 g, 63% yield).
References
[1] Patent: WO2012/30894, 2012, A1. Location in patent: Page/Page column 89-90
Ethyl 4-oxo-3,4-dihydrothieno[3,2-d]pyriMidine-2-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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