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3-(trifluoroMethyl)pyrazine-2-carboxylic acid

Product Name
3-(trifluoroMethyl)pyrazine-2-carboxylic acid
CAS No.
870787-06-7
Chemical Name
3-(trifluoroMethyl)pyrazine-2-carboxylic acid
Synonyms
3-(Trifluoromethyl)pyrazine-2-carb;3-(Trifluoromethyl)-2-pyrazinecarboxylic acid;3-(trifluoroMethyl)pyrazine-2-carboxylic acid;2-Pyrazinecarboxylic acid, 3-(trifluoromethyl)-
CBNumber
CB22654177
Molecular Formula
C6H3F3N2O2
Formula Weight
192.1
MOL File
870787-06-7.mol
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3-(trifluoroMethyl)pyrazine-2-carboxylic acid Property

Melting point:
147°(dec.)
Boiling point:
271.3±40.0℃ (760 Torr)
Density 
1.575±0.06 g/cm3 (20 ºC 760 Torr)
Flash point:
117.9±27.3℃
storage temp. 
2-8°C
pka
1.96±0.36(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
T899463
Product name
3-(Trifluoromethyl)pyrazine-2-carboxylicAcid
Packaging
100mg
Price
$265
Updated
2021/12/16
AK Scientific
Product number
3733AC
Product name
3-(Trifluoromethyl)pyrazine-2-carboxylicacid
Packaging
100mg
Price
$217
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0365105
Product name
3-(TRIFLUOROMETHYL)PYRAZINE-2-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$504.02
Updated
2021/12/16
AK Scientific
Product number
3733AC
Product name
3-(Trifluoromethyl)pyrazine-2-carboxylicacid
Packaging
5g
Price
$2364
Updated
2021/12/16
Ambeed
Product number
A155317
Product name
3-(Trifluoromethyl)pyrazine-2-carboxylicacid
Purity
97%
Packaging
100mg
Price
$107
Updated
2021/12/16
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3-(trifluoroMethyl)pyrazine-2-carboxylic acid Chemical Properties,Usage,Production

Uses

3-(Trifluoromethyl)pyrazine-2-carboxylic Acid is used as a reactant in synthesis and biological activity of a novel fungicide, (N-Biphenylyl)pyrazine Carboxamides.

Synthesis

870787-05-6

870787-06-7

Example 16. Preparation of 3-(trifluoromethyl)pyrazine-2-carboxylic acid (Compound No. 3-5) Methyl 3-(trifluoromethyl)pyrazine-2-carboxylate (700 mg, 3.4 mmol) was dissolved in a solvent mixture of ethanol-water (1:1, 10 mL, v/v), followed by addition of potassium hydroxide (300 mg). The reaction mixture was heated to reflux for 1 hour. Upon completion of the reaction, the reaction solution was concentrated under reduced pressure and the residue was diluted with water and washed with ethyl acetate. The aqueous phase was acidified with hydrochloric acid and extracted with ethyl acetate and the organic phase was washed with saturated brine. The combined organic phases were dried with anhydrous magnesium sulfate and concentrated under reduced pressure to give 409 mg of target compound crystals in 63% yield. Properties: melting point 130-134°C.

References

[1] Patent: EP1757595, 2007, A1. Location in patent: Page/Page column 24-25

3-(trifluoroMethyl)pyrazine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(trifluoroMethyl)pyrazine-2-carboxylic acid Suppliers

Shanghai AmasPharm Co., Ltd.
Tel
021-54540637 18621091017
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021-34978309
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sales@amaspharm.com
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China
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ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ:3470079902
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675141927@qq.com
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China
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Kohn & Shawn Pharmatech Co.,Ltd
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0931-4190454 13893344397
Fax
+86-931-8506154
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sales@kyxpharma.com
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China
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Cochemical Ltd.
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029-86115547 17791676824
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02151602123
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sales@cochemical.com
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China
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Amadis Chemical Company Limited
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571-89925085
Fax
0086-571-89925065
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sales@amadischem.com
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China
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Zhengzhou Huiju Chemical Co., Ltd.
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0371-55900031 18137872243
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2853979815@qq.com
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China
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Biokitchen
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donghuanwen@126.com
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China
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Capot Chemical Co.,Ltd.
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+86-(0)57185586718; +8613336195806
Fax
+86-571-85864795
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sales@capot.com
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China
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Aikon International Limited
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025-58859352 18068836627
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(5)02557626880
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dt3@aikonchem.com
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China
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Shanghai WangFa Chemical Technology Co., Ltd.
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13918479294
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-
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xiebenfa@163.com
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China
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4092
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View Lastest Price from 3-(trifluoroMethyl)pyrazine-2-carboxylic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3-(trifluoromethyl)pyrazine-2-carboxylic acid 870787-06-7
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
Longyan Tianhua Biological Technology Co., Ltd
Product
3-(trifluoroMethyl)pyrazine-2-carboxylic acid 870787-06-7
Price
US $30.00/Kg/Bag
Min. Order
25Kg/Bag
Purity
99%
Supply Ability
20 Tons
Release date
2020-11-13
Career Henan Chemical Co
Product
3-(trifluoroMethyl)pyrazine-2-carboxylic acid 870787-06-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-18

870787-06-7, 3-(trifluoroMethyl)pyrazine-2-carboxylic acidRelated Search:


  • 3-(trifluoroMethyl)pyrazine-2-carboxylic acid
  • 3-(Trifluoromethyl)-2-pyrazinecarboxylic acid
  • 2-Pyrazinecarboxylic acid, 3-(trifluoromethyl)-
  • 3-(Trifluoromethyl)pyrazine-2-carb
  • 870787-06-7