AZ 876
- Product Name
- AZ 876
- CAS No.
- 898800-26-5
- Chemical Name
- AZ 876
- Synonyms
- AZ 876;AZ 12260493;AZ-12260493.;AZ-876 (AZ876;AZ-876, AZ12260493;AZ876;AZ-876;AZ 876;AZ 876,Liver X receptor,AZ-876,LXR,Inhibitor,AZ876,inhibit;AZ876; AZ 876; AZ-876, AZ12260493; AZ 12260493; AZ-12260493.;2-tert-butyl-1,1-dioxo-5-phenyl-4-(4-piperidin-1-ylanilino)-1,2-thiazol-3-one;2-(tert-Butyl)-5-phenyl-4-((4-(piperidin-1-yl)phenyl)amino)isothiazol-3(2H)-one 1,1-dioxide
- CBNumber
- CB22667414
- Molecular Formula
- C24H29N3O3S
- Formula Weight
- 439.57
- MOL File
- 898800-26-5.mol
AZ 876 Property
- Boiling point:
- 605.3±65.0 °C(Predicted)
- Density
- 1.293±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- dmso:94.0(Max Conc. mg/mL);213.84(Max Conc. mM)
- form
- A solid
- pka
- 5.80±0.20(Predicted)
- color
- Yellow to orange
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CS-5724
- Product name
- AZ876
- Purity
- 99.89%
- Packaging
- 1mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CS-5724
- Product name
- AZ876
- Purity
- 99.89%
- Packaging
- 5mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- CS-5724
- Product name
- AZ876
- Purity
- 99.89%
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- CS-5724
- Product name
- AZ876
- Purity
- 99.89%
- Packaging
- 50mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- CS-5724
- Product name
- AZ876
- Purity
- 99.89%
- Packaging
- 100mg
- Price
- $450
- Updated
- 2021/12/16
AZ 876 Chemical Properties,Usage,Production
Uses
AZ876 is a potent and high-affinity LXR agonist. AZ876 displays 25-fold and 2.5-fold more potent than GW3965 (HY-10627) on human (h)LXRα and hLXRβ respectively[1][2].
References
[1] Cannon MV et al. The liver X receptor agonist AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects. Eur J Heart Fail. 2015 Mar;17(3):273-82. DOI:10.1002/ejhf.243
[2] van der Hoorn J et al. Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels. Br J Pharmacol. 2011 Apr;162(7):1553-63. DOI:10.1111/j.1476-5381.2010.01168.x
AZ 876 Preparation Products And Raw materials
Raw materials
Preparation Products
AZ 876 Suppliers
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View Lastest Price from AZ 876 manufacturers
- Product
- AZ876 898800-26-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- Min98% HPLC
- Supply Ability
- g/kg/ton
- Release date
- 2020-01-01