ChemicalBook > CAS DataBase List > AZ 876

AZ 876

Product Name
AZ 876
CAS No.
898800-26-5
Chemical Name
AZ 876
Synonyms
AZ 876;AZ 12260493;AZ-12260493.;AZ-876 (AZ876;AZ-876, AZ12260493;AZ876;AZ-876;AZ 876;AZ 876,Liver X receptor,AZ-876,LXR,Inhibitor,AZ876,inhibit;AZ876; AZ 876; AZ-876, AZ12260493; AZ 12260493; AZ-12260493.;2-tert-butyl-1,1-dioxo-5-phenyl-4-(4-piperidin-1-ylanilino)-1,2-thiazol-3-one;2-(tert-Butyl)-5-phenyl-4-((4-(piperidin-1-yl)phenyl)amino)isothiazol-3(2H)-one 1,1-dioxide
CBNumber
CB22667414
Molecular Formula
C24H29N3O3S
Formula Weight
439.57
MOL File
898800-26-5.mol
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AZ 876 Property

Boiling point:
605.3±65.0 °C(Predicted)
Density 
1.293±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
dmso:94.0(Max Conc. mg/mL);213.84(Max Conc. mM)
form 
A solid
pka
5.80±0.20(Predicted)
color 
Yellow to orange
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-5724
Product name
AZ876
Purity
99.89%
Packaging
1mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-5724
Product name
AZ876
Purity
99.89%
Packaging
5mg
Price
$100
Updated
2021/12/16
ChemScene
Product number
CS-5724
Product name
AZ876
Purity
99.89%
Packaging
10mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-5724
Product name
AZ876
Purity
99.89%
Packaging
50mg
Price
$250
Updated
2021/12/16
ChemScene
Product number
CS-5724
Product name
AZ876
Purity
99.89%
Packaging
100mg
Price
$450
Updated
2021/12/16
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AZ 876 Chemical Properties,Usage,Production

Uses

AZ876 is a potent and high-affinity LXR agonist. AZ876 displays 25-fold and 2.5-fold more potent than GW3965 (HY-10627) on human (h)LXRα and hLXRβ respectively[1][2].

References

[1] Cannon MV et al. The liver X receptor agonist AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects. Eur J Heart Fail. 2015 Mar;17(3):273-82. DOI:10.1002/ejhf.243
[2] van der Hoorn J et al. Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE*3Leiden mice without affecting liver or plasma triglyceride levels. Br J Pharmacol. 2011 Apr;162(7):1553-63. DOI:10.1111/j.1476-5381.2010.01168.x

AZ 876 Preparation Products And Raw materials

Raw materials

Preparation Products

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AZ 876 Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
Tel
17702719238 18971495150;
Email
sales@sun-shinechem.com
Country
China
ProdList
1150
Advantage
64
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4769
Advantage
55
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39999
Advantage
60
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4817
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
86249
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
9695
Advantage
55
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View Lastest Price from AZ 876 manufacturers

Career Henan Chemical Co
Product
AZ876 898800-26-5
Price
US $1.00/KG
Min. Order
1KG
Purity
Min98% HPLC
Supply Ability
g/kg/ton
Release date
2020-01-01

898800-26-5, AZ 876Related Search:


  • AZ 876
  • 2-(1,1-Dimethylethyl)-5-phenyl-4-[[4-(1-piperidinyl)phenyl]amino]-3(2H)-isothiazolone 1,1-dioxide
  • AZ876;AZ-876;AZ 876
  • 2-tert-butyl-1,1-dioxo-5-phenyl-4-(4-piperidin-1-ylanilino)-1,2-thiazol-3-one
  • AZ 12260493
  • AZ-12260493.
  • AZ-876, AZ12260493
  • AZ876; AZ 876; AZ-876, AZ12260493; AZ 12260493; AZ-12260493.
  • 3(2H)-Isothiazolone, 2-(1,1-dimethylethyl)-5-phenyl-4-[[4-(1-piperidinyl)phenyl]amino]-, 1,1-dioxide
  • AZ 876,Liver X receptor,AZ-876,LXR,Inhibitor,AZ876,inhibit
  • 2-(tert-Butyl)-5-phenyl-4-((4-(piperidin-1-yl)phenyl)amino)isothiazol-3(2H)-one 1,1-dioxide
  • AZ-876 (AZ876
  • 898800-26-5
  • APIS
  • API