S-EMCA

Product Name: S-EMCA
CAS No.: 1199796-29-6
Chemical Name: S-EMCA
Synonyms: S-EMCA;CS-1212;INT-777;INT777,INT 777;INT-777, S-EMCA;6α-Ethyl-23(S)-Methylcholic acid;6a-Ethyl-23(S)-methylcholic acid;6alpha-Ethyl-23(S)-methylcholic acid;Obeticholic Acid Impurity 49(S-EMCA);Acetylcysteine Impurity 49(D-Cysteine)
CBNumber: CB22667494
Molecular Formula: C27H46O5
Formula Weight: 450.65114
MOL File: 1199796-29-6.mol

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S-EMCA Property

Melting point:: 150-152℃
Boiling point:: 602.8±55.0 °C(Predicted)
Density: 1.128±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF:30.0(Max Conc. mg/mL);66.57(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.11(Max Conc. mM)
DMSO:25.5(Max Conc. mg/mL);56.58(Max Conc. mM)
Ethanol:37.5(Max Conc. mg/mL);83.21(Max Conc. mM)
pka: 4.80±0.21(Predicted)
form: Powder
color: White to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 17678
Product name: INT-777
Purity: ≥95%
Packaging: 500μg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 17678
Product name: INT-777
Purity: ≥95%
Packaging: 1mg
Price: $230
Updated: 2024/03/01

TRC

Product number: I666630
Product name: 6α-Ethyl-23(S)-methylcholicAcid
Packaging: 25mg
Price: $2035
Updated: 2021/12/16

ApexBio Technology

Product number: B4672
Product name: INT-777
Packaging: 50mg
Price: $2250
Updated: 2021/12/16

ChemScene

Product number: CS-3199
Product name: INT-777
Purity: 100.00%
Packaging: 100mg
Price: $2520
Updated: 2021/12/16

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S-EMCA Chemical Properties,Usage,Production

Uses

INT 777 is an inhibitor of TGR5 receptor, which is a transmembrane G protein-coupled receptor expressed in brown adipose tissue and muscle and activated by bile acid.

S-EMCA Preparation Products And Raw materials

Raw materials

Preparation Products

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S-EMCA Suppliers

Canada 1 China 41 India 1 United States 8 Global 51

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

LETOPHARM LIMITED

Tel: +86-21-5821 5861
Fax: +86-21-5106 2861
Email: sales@letopharm.com
Country: China
ProdList: 2384
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4512
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

Guangzhou QiYun Biotechnology Co., Ltd.

Tel: 020-61288194 61288195
Fax: 020-61288700
Email: 505721671@qq.com
Country: China
ProdList: 3866
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

1199796-29-6, S-EMCARelated Search:

6α-Ethyl-23(S)-Methylcholic acid

INT-777

S-EMCA

6alpha-Ethyl-23(S)-methylcholic acid

6a-Ethyl-23(S)-methylcholic acid

CS-1212

INT-777, S-EMCA

Cholane-23-carboxylic acid, 6-ethyl-3,7,12-trihydroxy-, (3α,5β,6α,7α,12α,23S)-

INT777,INT 777

Obeticholic Acid Impurity 49(S-EMCA)

Acetylcysteine Impurity 49(D-Cysteine)

(2S,4R)-4-((3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-Ethyl-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylpentanoic acid

(2S,4R)-4-[(1R,3aS,3bR,4R,5R,5aS,7R,9aS,9bS,11S,11aR)-5-ethyl-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2-methylpentanoic acid

1199796-29-6