ChemicalBook > CAS DataBase List > S-EMCA

S-EMCA

Product Name
S-EMCA
CAS No.
1199796-29-6
Chemical Name
S-EMCA
Synonyms
S-EMCA;CS-1212;INT-777;INT777,INT 777;INT-777, S-EMCA;6α-Ethyl-23(S)-Methylcholic acid;6a-Ethyl-23(S)-methylcholic acid;6alpha-Ethyl-23(S)-methylcholic acid;Obeticholic Acid Impurity 49(S-EMCA);Acetylcysteine Impurity 49(D-Cysteine)
CBNumber
CB22667494
Molecular Formula
C27H46O5
Formula Weight
450.65114
MOL File
1199796-29-6.mol
More
Less

S-EMCA Property

Melting point:
150-152℃
Boiling point:
602.8±55.0 °C(Predicted)
Density 
1.128±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF:30.0(Max Conc. mg/mL);66.57(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.11(Max Conc. mM)
DMSO:25.5(Max Conc. mg/mL);56.58(Max Conc. mM)
Ethanol:37.5(Max Conc. mg/mL);83.21(Max Conc. mM)
pka
4.80±0.21(Predicted)
form 
Powder
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
17678
Product name
INT-777
Purity
≥95%
Packaging
500μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
17678
Product name
INT-777
Purity
≥95%
Packaging
1mg
Price
$230
Updated
2024/03/01
TRC
Product number
I666630
Product name
6α-Ethyl-23(S)-methylcholicAcid
Packaging
25mg
Price
$2035
Updated
2021/12/16
ApexBio Technology
Product number
B4672
Product name
INT-777
Packaging
50mg
Price
$2250
Updated
2021/12/16
ChemScene
Product number
CS-3199
Product name
INT-777
Purity
100.00%
Packaging
100mg
Price
$2520
Updated
2021/12/16
More
Less

S-EMCA Chemical Properties,Usage,Production

Uses

INT 777 is an inhibitor of TGR5 receptor, which is a transmembrane G protein-coupled receptor expressed in brown adipose tissue and muscle and activated by bile acid.

S-EMCA Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

S-EMCA Suppliers

Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7553
Advantage
61
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3421
Advantage
58
LETOPHARM LIMITED
Tel
+86-21-5821 5861
Fax
+86-21-5106 2861
Email
sales@letopharm.com
Country
China
ProdList
2384
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4153
Advantage
55
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3868
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4662
Advantage
60

1199796-29-6, S-EMCARelated Search:


  • 6α-Ethyl-23(S)-Methylcholic acid
  • INT-777
  • S-EMCA
  • 6alpha-Ethyl-23(S)-methylcholic acid
  • 6a-Ethyl-23(S)-methylcholic acid
  • CS-1212
  • INT-777, S-EMCA
  • Cholane-23-carboxylic acid, 6-ethyl-3,7,12-trihydroxy-, (3α,5β,6α,7α,12α,23S)-
  • INT777,INT 777
  • Obeticholic Acid Impurity 49(S-EMCA)
  • Acetylcysteine Impurity 49(D-Cysteine)
  • 1199796-29-6