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S-EMCA

Product Name
S-EMCA
CAS No.
1199796-29-6
Chemical Name
S-EMCA
Synonyms
S-EMCA;CS-1212;INT-777;INT777,INT 777;INT-777, S-EMCA;6α-Ethyl-23(S)-Methylcholic acid;6a-Ethyl-23(S)-methylcholic acid;6alpha-Ethyl-23(S)-methylcholic acid;Obeticholic Acid Impurity 49(S-EMCA);Acetylcysteine Impurity 49(D-Cysteine)
CBNumber
CB22667494
Molecular Formula
C27H46O5
Formula Weight
450.65114
MOL File
1199796-29-6.mol
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S-EMCA Property

Melting point:
150-152℃
Boiling point:
602.8±55.0 °C(Predicted)
Density 
1.128±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF:30.0(Max Conc. mg/mL);66.57(Max Conc. mM)
DMF:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.11(Max Conc. mM)
DMSO:25.5(Max Conc. mg/mL);56.58(Max Conc. mM)
Ethanol:37.5(Max Conc. mg/mL);83.21(Max Conc. mM)
pka
4.80±0.21(Predicted)
form 
Powder
color 
White to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17678
Product name
INT-777
Purity
≥95%
Packaging
500μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
17678
Product name
INT-777
Purity
≥95%
Packaging
1mg
Price
$230
Updated
2024/03/01
TRC
Product number
I666630
Product name
6α-Ethyl-23(S)-methylcholicAcid
Packaging
25mg
Price
$2035
Updated
2021/12/16
ApexBio Technology
Product number
B4672
Product name
INT-777
Packaging
50mg
Price
$2250
Updated
2021/12/16
ChemScene
Product number
CS-3199
Product name
INT-777
Purity
100.00%
Packaging
100mg
Price
$2520
Updated
2021/12/16
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S-EMCA Chemical Properties,Usage,Production

Uses

INT 777 is an inhibitor of TGR5 receptor, which is a transmembrane G protein-coupled receptor expressed in brown adipose tissue and muscle and activated by bile acid.

S-EMCA Preparation Products And Raw materials

Raw materials

Preparation Products

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S-EMCA Suppliers

MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

1199796-29-6, S-EMCARelated Search:


  • 6α-Ethyl-23(S)-Methylcholic acid
  • INT-777
  • S-EMCA
  • 6alpha-Ethyl-23(S)-methylcholic acid
  • 6a-Ethyl-23(S)-methylcholic acid
  • CS-1212
  • INT-777, S-EMCA
  • Cholane-23-carboxylic acid, 6-ethyl-3,7,12-trihydroxy-, (3α,5β,6α,7α,12α,23S)-
  • INT777,INT 777
  • Obeticholic Acid Impurity 49(S-EMCA)
  • Acetylcysteine Impurity 49(D-Cysteine)
  • (2S,4R)-4-((3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-Ethyl-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylpentanoic acid
  • (2S,4R)-4-[(1R,3aS,3bR,4R,5R,5aS,7R,9aS,9bS,11S,11aR)-5-ethyl-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2-methylpentanoic acid
  • 1199796-29-6