ChemicalBook > CAS DataBase List > Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-

Product Name
Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-
CAS No.
1017606-66-4
Chemical Name
Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-
Synonyms
CS-1271;LPA2-IN-1;LPA2 antagonist 1;LPA-2 antagonist 1,LPA2 antagonist 1;N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine;(S)-N-(1-(4-((3,4-Dichlorophenyl)sulfonyl)piperazin-1-yl)propan-2-yl)-7-methylthieno[3,2-d]pyrimidin-4-amine;Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-
CBNumber
CB22668325
Molecular Formula
C20H23Cl2N5O2S2
Formula Weight
500.46
MOL File
1017606-66-4.mol
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Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Property

Boiling point:
684.6±65.0 °C(Predicted)
Density 
1.453±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.33 mg/ml
form 
Powder
pka
6.52±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22051
Product name
LPA2 Antagonist 1
Purity
≥98%
Packaging
1mg
Price
$236
Updated
2024/03/01
Cayman Chemical
Product number
22051
Product name
LPA2 Antagonist 1
Purity
≥98%
Packaging
5mg
Price
$395
Updated
2024/03/01
Cayman Chemical
Product number
22051
Product name
LPA2 Antagonist 1
Purity
≥98%
Packaging
10mg
Price
$656
Updated
2024/03/01
TRC
Product number
N926243
Product name
N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-3103
Product name
LPA2antagonist1
Purity
99.12%
Packaging
5mg
Price
$420
Updated
2021/12/16
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Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Chemical Properties,Usage,Production

Description

LPA2 antagonist 1 is an antagonist of lysophosphatidic acid receptor 2 (LPA2; IC50 = 17 nM). It is selective for LPA2 over LPA1 and LPA3 (IC50s = >50 μM). LPA2 antagonist 1 inhibits HGF-induced phosphorylation of ERK and proliferation of HCT116 colon cancer cells in a concentration-dependent manner.

Uses

N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine is a Lpa2 protein antagonists.

Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl- Suppliers

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1017606-66-4, Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-Related Search:


  • CS-1271
  • LPA2-IN-1
  • Thieno[3,2-d]pyriMidin-4-aMine, N-[(1S)-2-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]-1-Methylethyl]-7-Methyl-
  • LPA2 antagonist 1
  • N-[(2S)-1-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine
  • (S)-N-(1-(4-((3,4-Dichlorophenyl)sulfonyl)piperazin-1-yl)propan-2-yl)-7-methylthieno[3,2-d]pyrimidin-4-amine
  • LPA-2 antagonist 1,LPA2 antagonist 1
  • 1017606-66-4
  • C20H23Cl2N5O2S2