Finasteride (acetate)
- Product Name
- Finasteride (acetate)
- CAS No.
- 222989-99-3
- Chemical Name
- Finasteride (acetate)
- Synonyms
- MK-906 acetate;Finasteride (acetate)
- CBNumber
- CB22677068
- Molecular Formula
- C25H40N2O4
- Formula Weight
- 432.61
- MOL File
- 222989-99-3.mol
Finasteride (acetate) Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
N-Bromosuccinimide Price
- Product number
- B1195
- Product name
- Finasterideacetate
- Packaging
- 100mg
- Price
- $81
- Updated
- 2021/12/16
- Product number
- B1195
- Product name
- Finasterideacetate
- Packaging
- 200mg
- Price
- $139
- Updated
- 2021/12/16
- Product number
- CD31002618
- Product name
- Finasterideacetate
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $51
- Updated
- 2021/12/16
Finasteride (acetate) Chemical Properties,Usage,Production
Uses
Finasteride (MK-906) acetate is a potent and competitive 5α-reductase inhibitor, with an IC50 of 4.2 nM for type II 5α-reductase. Finasteride acetate has approximately a 100-fold greater affinity for type II 5α-reductase enzyme than for the type I enzyme. Finasteride acetate can be used for the research of benign prostatic hyperplasia (BPH) and androgenic alopecia[1][2][3].
Biological Activity
finasteride acetate(mk-906,proscar and propecia) is a specific inhibitor of 5α-reductase and a drug of synthetic used in the benign prostatic hyperplasia (bph) and the male pattern baldness (mpb) [1].
in vivo
finasteride acetate (mk-906, proscar and propecia) has been reported to significant reduce the concentration of dht in prostatic tissue without side effects in pharmacologic experiments in rats and dogs. in addition, finasteride acetate has shown the inhibition of 5α-reductase activity resulted in significant inhibition of dht levels. finasteride acetate has also shown the effect on reducing prostate volume in clinical experiments [1]. finasteride acetate has been revealed to have the function to inhibit glucuronyl transferase in vitro test using rat prostate tissue [2].
References
[1] stoner e.the clinical development of a 5 alpha-reductase inhibitor, finasteride. j steroid biochem mol biol. 1990 nov 20;37(3):375-8.
[2] rittmaster rs1, stoner e, thompson dl, nance d, lasseter kc.effect of mk-906, a specific 5 alpha-reductase inhibitor, on serum androgens and androgen conjugates in normal men. j androl. 1989 jul-aug;10(4):259-62.
Finasteride (acetate) Preparation Products And Raw materials
Raw materials
Preparation Products
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