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Nitrazolam

Product Name
Nitrazolam
CAS No.
28910-99-8
Chemical Name
Nitrazolam
Synonyms
NitrazolaM;Nitrazolame;Nitrazolam 98%;1-Methyl-8-nitro-6-phenyl-4H-2,3,5,10b-tetraaza-benzo[e]azulene;1-Methyl-8-nitro-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine;1-Methyl-8-nitro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine;4H-[1,2,4]Triazolo[4,3-a][1,4]benzodiazepine, 1-methyl-8-nitro-6-phenyl-;1-methyl-8-nitro-6-phenyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepine
CBNumber
CB22681342
Molecular Formula
C17H13N5O2
Formula Weight
319.32
MOL File
28910-99-8.mol
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Nitrazolam Property

Boiling point:
550.2±60.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
solubility 
DMF: 30 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml; Methanol: 1 mg/ml
pka
1.96±0.40(Predicted)
form 
Solid
color 
Yellow
InChI
InChI=1S/C17H13N5O2/c1-11-19-20-16-10-18-17(12-5-3-2-4-6-12)14-9-13(22(23)24)7-8-15(14)21(11)16/h2-9H,10H2,1H3
InChIKey
OYRPNABWTHDOFK-UHFFFAOYSA-N
SMILES
N12C(C)=NN=C1CN=C(C1=CC=CC=C1)C1=CC([N+]([O-])=O)=CC=C12
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22620
Product name
Nitrazolam
Packaging
1mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
22620
Product name
Nitrazolam
Packaging
5mg
Price
$356
Updated
2024/03/01
AK Scientific
Product number
0365CZ
Product name
Nitrazolam
Packaging
1mg
Price
$187
Updated
2021/12/16
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Nitrazolam Chemical Properties,Usage,Production

Description

Nitrazolam is classified as a novel benzodiazepine, although its synthesis and activity have been previously described in the literature. Benzodiazepines are central nervous system depressants. Novel benzodiazepines, often pirated from early drug discovery or pharmaceutical studies, have appeared on the novel and illicit drug markets in recent years. These substances have caused adverse events, including deaths, as described in the literature. Nitrazolam is structurally similar to traditional benzodiazepines nitrazepam and alprazolam, Schedule IV substances in the United States, as well as the novel benzodiazepines flunitrazolam and clonazelam. 

Uses

Nitrazolam is a designer benzodiazepine substance which displays psychoactive activity. May be used in the self-treatment of anxiety or mental disorders.

Biological Functions

Nitrazepam is a powerful drug that belongs to the Benzodiazepine family. It is primarily used to treat chronic sleeplessness and anxiety. The drug works basically by relaxing the brain and restoring the normal sleep-wake cycle, making people feel calmer and energised. It is a heavy-duty drug that has strong sedative and muscle relaxant properties. Hence it must be used with caution.

Clinical Use

Nitrazolam is primarily used as an anticonvulsant in children. It is also still used in the most severe and debilitating cases of insomnia in an inpatient setting or in short term outpatient treatment. Hypnotic benzodiazepines estazolam and nitrazepam are used more frequently than nimetazepam for this purpose. The foremost use of Nitrazepam is to treat insomnia, which includes an inability to fall asleep and waking up at night regularly. It’s also prescribed for restless legs syndrome, anxiety disorder, and depression. 

Nitrazolam Preparation Products And Raw materials

Raw materials

Preparation Products

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Nitrazolam Suppliers

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View Lastest Price from Nitrazolam manufacturers

Dorne Chemical Technology co. LTD
Product
NitrazolaM 28910-99-8
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
Hebei Miaoyin Technology Co.,Ltd
Product
NitrazolaM 28910-99-8
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000
Release date
2023-04-18
Shandong Hanjiang Chemical Co., Ltd
Product
Nitrazolam 28910-99-8
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10T
Release date
2024-01-12

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