IMiquiMod (Maleate)
- Product Name
- IMiquiMod (Maleate)
- CAS No.
- 896106-16-4
- Chemical Name
- IMiquiMod (Maleate)
- Synonyms
- IMiquiMod (Maleate);1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-amine maleate
- CBNumber
- CB22682006
- Molecular Formula
- C18H20N4O4
- Formula Weight
- 356.3758
- MOL File
- 896106-16-4.mol
IMiquiMod (Maleate) Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Powder
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- WKB10616
- Product name
- Imiquimod maleate
- Packaging
- 0.1g
- Price
- $171.88
- Updated
- 2026/06/05
- Product number
- WKB10616
- Product name
- Imiquimod maleate
- Packaging
- 0.25g
- Price
- $343.75
- Updated
- 2026/06/05
- Product number
- WKB10616
- Product name
- Imiquimod maleate
- Packaging
- 0.5g
- Price
- $550
- Updated
- 2026/06/05
- Product number
- WKB10616
- Product name
- Imiquimod maleate
- Packaging
- 1g
- Price
- $893.75
- Updated
- 2026/06/05
- Product number
- WKB10616
- Product name
- Imiquimod maleate
- Packaging
- 2g
- Price
- $1237.5
- Updated
- 2026/06/05
IMiquiMod (Maleate) Chemical Properties,Usage,Production
Uses
Imiquimod maleate (R 837 maleate), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod maleate exhibits antiviral and antitumor effects in vivo. Imiquimod maleate can be used for the research of external genital, perianal warts, cancer and COVID-19[1][2].
in vivo
In animal models, imiquimod stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete cytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α[1].
IC 50
TLR7; HSV-1
References
[1] Athina Angelopoulou, et al. Imiquimod - A toll like receptor 7 agonist - Is an ideal option for management of COVID 19. Environ Res. 2020 Sep; 188: 109858. DOI:10.1016/j.envres.2020.109858
[2] Aditya K Gupta, et al. Imiquimod: a review. J Cutan Med Surg. Nov-Dec 2002;6(6):554-60. DOI:10.1007/s10227-001-0134-6
[3] Yuji Kan, et al. Imiquimod suppresses propagation of herpes simplex virus 1 by upregulation of cystatin A via the adenosine receptor A1 pathway. J Virol. 2012 Oct;86(19):10338-46. DOI:10.1128/JVI.01196-12
[4] Michael P Schn, et al. The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion. J Invest Dermatol. 2006 Jun;126(6):1338-47. DOI:10.1038/sj.jid.5700286
IMiquiMod (Maleate) Preparation Products And Raw materials
Raw materials
Preparation Products
IMiquiMod (Maleate) Suppliers
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