5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid

Product Name: 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
CAS No.: 1052114-81-4
Chemical Name: 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid
Synonyms: 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic ac;5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid;5-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-Pyridinecarboxylic acid;3-Pyridinecarboxylic acid, 5-(4-fluorophenyl)-1,4-dihydro-4-oxo-
CBNumber: CB22684499
Molecular Formula: C12H8FNO3
Formula Weight: 233.2
MOL File: 1052114-81-4.mol

More

Less

5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid Property

Boiling point:: 423.3±45.0 °C(Predicted)
Density: 1.437±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: -0.34±0.20(Predicted)
Appearance: White to light yellow Solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 8710DP
Product name: 5-(4-Fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylicacid
Packaging: 1g
Price: $271
Updated: 2021/12/16

Chemenu

Product number: CM247530
Product name: 5-(4-Fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylicacid
Purity: 97%
Packaging: 1g
Price: $542
Updated: 2021/12/16

Crysdot

Product number: CD11359500
Product name: 5-(4-Fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylicacid
Purity: 97%
Packaging: 1g
Price: $574
Updated: 2021/12/16

Alichem

Product number: 1052114814
Product name: 5-(4-Fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylicacid
Packaging: 1g
Price: $614.8
Updated: 2021/12/16

Ambeed

Product number: A113559
Product name: 5-(4-Fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylicacid
Purity: 97%
Packaging: 100mg
Price: $43
Updated: 2021/12/16

More

Less

5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid Chemical Properties,Usage,Production

Synthesis

1052114-80-3

1052114-81-4

Example A8: Example A7 (0.750 g, 2.87 mmol) was suspended in 3 M NaOH aqueous solution (7.5 mL, 22.50 mmol) and heated to reflux at 100 °C for 1.5 hrs. Upon completion of the reaction, the mixture was cooled to room temperature and slowly acidified to pH 2 with 3 M aqueous HCl. The precipitated white solid was collected by vacuum filtration and washed with deionized water and dried to afford 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid (669 mg, 100% yield). The product was analyzed by mass spectrometry (ESI), m/z: 234.1 ([M + H]+).

References

[1] Patent: WO2014/145004, 2014, A1. Location in patent: Paragraph 0111
[2] Journal of Medicinal Chemistry, 2008, vol. 51, # 17, p. 5330 - 5341
[3] Patent: WO2009/94417, 2009, A1. Location in patent: Page/Page column 28; 35-36
[4] Patent: WO2014/713, 2014, A1. Location in patent: Page/Page column 38

5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid Suppliers

China 25 India 1 United States 1 Global 27

Tongchuang Pharma(Suzhou). Co., Ltd.

Tel: 0512-63263366 18912765016
Fax: 0512-6326 3366
Email: tongtf110@sina.com
Country: China
ProdList: 993
Advantage: 62

Hangzhou Trylead Chemical Technology Co.,LTD

Tel: 0571-87086220 13516718938
Fax: 0571-87012927
Email: zyf@trylead-chem.com
Country: China
ProdList: 310
Advantage: 64

NINGBO INNO PHARMCHEM CO.,LTD.

Tel: 86-574-27787657
Fax: 86-574-27912196
Email: info@dearchem.com
Country: China
ProdList: 4613
Advantage: 58

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q2635253576
Fax: QQ3382968513
Email: hailey@shsendpharm.com
Country: China
ProdList: 2081
Advantage: 55

Shanghai Brain Biotechnology Co., Ltd.

Tel: 13564638271
Fax: 021-68948280
Email: shhjiang1977@163.com
Country: China
ProdList: 2987
Advantage: 55

Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2991
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Nanjing Easichem Co. ltd.

Tel: 18061688856
Email: easichem@126.com
Country: China
ProdList: 477
Advantage: 58

Jinan ponder chemical co. LTD

Tel: 0531-0000
Email: thinklifescience@163.com
Country: China
ProdList: 19689
Advantage: 58

Tianjin Nuokang Pharmaceutical Technology Co., Ltd.

Tel: 022-23989838 13810451150
Email: 44766350@qq.com
Country: China
ProdList: 2349
Advantage: 58

Shanghai Weiyuan Technology Co., Ltd.

Tel: 13024122785 17356341931
Email: sales@shweiyuan.cn
Country: China
ProdList: 280
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

cjbscvictory

Tel: 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10503
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Hubei Chenxin Pharmaceutical Co., Ltd.

Tel: 18696113233
Fax: QQ:2544920688
Email: like1076463918@163.com
Country: China
ProdList: 3130
Advantage: 58

ChemeGen

Tel: 18818260767
Fax: QQ 3610331285
Email: 2625930290@qq.com
Country: China
ProdList: 6973
Advantage: 58

Shanghai daoyang technology co., ltd

Tel: QQ:3150471267 13381681725
Email: 3150471267@qq.com
Country: China
ProdList: 464
Advantage: 58

Henan Weitixi Chemical Technology Co., Ltd

Tel: 0371-53370800 18037197114
Email: 2853031799@qq.com
Country: China
ProdList: 9892
Advantage: 58

HUBEI HICKS BIOCHEMICAL CO.,LTD

Tel: 18696113233
Email: 15927219311@163.com
Country: China
ProdList: 1660
Advantage: 58

Suzhou Qihang Biotechnology Co., Ltd

Tel: 18151111370
Email: 1046215251@qq.com
Country: China
ProdList: 8718
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29995
Advantage: 58

Shenzhen Zuoke Biotechnology Co., Ltd.

Tel: 13532174601
Country: CHINA
ProdList: 109
Advantage: 58

Debye Scientific Corporation

Tel: --
Fax: --
Country: China
ProdList: 6891
Advantage: 50

1052114-81-4, 5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acidRelated Search:

5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid

3-Pyridinecarboxylic acid, 5-(4-fluorophenyl)-1,4-dihydro-4-oxo-

5-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-Pyridinecarboxylic acid

5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic ac

1052114-81-4